神经药理学报2024，Vol.14Issue(2)：54-58,5.DOI:10.3969/j.issn.2095-1396.2024.02.009
姜黄素纳米制剂研究进展
Research Progress of Curcumin Nano-Preparations
摘要
Abstract
Curcumin(Cur)is a diketone compound extracted from the rhizomes of the genus turmeric,which has a wide range of pharmacological activities such as antioxidant,anti-inflammatory,anti-tumor,and neuroprotection,but has low solubility,short half-life,low bioavailability,difficult to penetrate the blood-brain barrier and other shortcomings limit its clinical application.In recent years,it has been prepared into liposomes,solid dispersions,polymer nanoparticles,polymer micelles,nanosuspensions,etc.,which significantly improved the solubility,bioavailability and targeting of Cur,and improved drug activity.This article reviewed the nano-preparations of Cur,aiming to provide references for its further research and development.关键词
姜黄素/纳米制剂/研究进展Key words
curcumin/nano-preparation/research progress分类
医药卫生引用本文复制引用
袁鑫茹,张丹参..姜黄素纳米制剂研究进展[J].神经药理学报,2024,14(2):54-58,5.基金项目
河北省重点研发计划项目生物医药专项(No.20372509D) （No.20372509D）
河北省自然科学基金项目(No.H2020208032) （No.H2020208032）
