佛山科学技术学院学报(自然科学版)2024,Vol.42Issue(4):64-69,6.
摩擦纳米发电机贴片促进成纤维细胞增殖研究
Study on promotion of fibroblast proliferation by triboelectric nanogenerator patch
摘要
Abstract
Objective A high-performance triboelectric nanogenerator(TENG)patch was constructed to generate electric field for regulating fibroblast proliferation and scratch healing.Methods A TENG with patch type was constructed by improving the material and structure,and a high-intensity electric field was generated by combining with the interdigital electrode for cell proliferation and cell scratch healing of fibroblasts.Results The open circuit voltage of the 4 cm×4 cm TENG patch was 200 V,the short circuit current was 25 μA,and the transfer charge was 35 nC.The proliferation of fibroblasts and the healing of fibroblast scratches were obviously promoted by electric field stimulation,which was formed by 1 V AC voltage output of the TENG combined with interdigital electrode.Conclusion As a new type of bioenergy harvesting device,TENG could convert mechanical energy into electrical energy.The prepared TENG patch acted as an electric field source to regulate cell activity,which provided a powerful support for tissue repair.关键词
摩擦纳米发电机/成纤维细胞/组织修复/电场Key words
triboelectric nanogenerator/fibroblast/tissue repair/electric field分类
医药卫生引用本文复制引用
赵超超,方菊,黄凯怡,谢伊婷,杨安平..摩擦纳米发电机贴片促进成纤维细胞增殖研究[J].佛山科学技术学院学报(自然科学版),2024,42(4):64-69,6.基金项目
国家自然科学基金资助项目(82001981) (82001981)
广东大学生科技创新培育专项资金资助项目(pdjh2023b0553) (pdjh2023b0553)
佛山市自筹经费类科技创新项目(2320001007516) (2320001007516)