超高效液相色谱-四极杆-飞行时间高分辨质谱用于化妆品中15种前列腺素类似物的快速筛查和测定OA北大核心CSTPCD
Rapid Screening and Determination of 15 Prostaglandin Analogues in Cosmetics by Ultra Performance Liquid Chromatography-Quadru-pole-Time-of-flight High-resolution Mass Spectrometry
建立了超高效液相色谱-四极杆-飞行时间高分辨质谱(UPLC-Q-TOF MS)快速筛查和测定化妆品中15种前列腺素类似物的方法.样品以饱和氯化钠作为分散剂(蜡质类样品以四氢呋喃分散),经乙腈提取,离心取上清液过滤后,采用Poroshell 120 EC-C18柱(150 mm×3.0 mm,2.7 μm)分离,以5 mmol/L甲酸铵(含0.1％甲酸)-乙腈为流动相梯度洗脱.在ESI正离子模式下,采用Targeted MS/MS模式采集15种前列…查看全部>>
In this study,an ultra performance liquid chromatography-quadrupole-time-of-flight high-resolution mass spectrometry(UPLC-Q-TOF MS)method was developed for the rapid screening and quantitative analysis of 15 prostaglandin analogues in cosmetics.The analytes in sample were dis-persed in saturated sodium chloride solution(wax samples were dispersed with tetrahydrofuran),then extracted with acetonitrile.After centrifugation and filtration,the UPLC separat…查看全部>>
陈安丽;张静;黄子沣;严小红
广州市药品检验所,广东 广州 510160广州市药品检验所,广东 广州 510160广州市药品检验所,广东 广州 510160广州市药品检验所,广东 广州 510160
化学
超高效液相色谱-四极杆-飞行时间高分辨质谱快速筛查化妆品前列腺素类似物
ultra performance liquid chromatography-quadrupole-time-of-flight high-resolution mass spectrometryrapid screeningcosmeticsprostaglandin analogues
《分析测试学报》 2024 (7)
1011-1017,7
广州市市场监督管理局科技项目(2022kj28)
评论