高效液相色谱法测定鸡蛋中25种咪唑类兽药及其代谢物残留OA北大核心CSTPCD
Determination of 25 Imidazole Veterinary Drugs and Their Metabo-lites in Eggs by High Performance Liquid Chromatography
建立了高效液相色谱(HPLC)测定鸡蛋中25种咪唑类兽药及其代谢物残留的分析方法.鸡蛋液经乙腈提取并浓缩后,采用Oasis PRIME HLB固相萃取柱净化,以甲醇和水为流动相进行梯度洗脱,采用ZORB-AXSB-Aq(250mm×4.6mm,5 μm)色谱柱分离,二极管阵列检测器(DAD)检测,外标法定量.实验结果表明,25种目标化合物在各自质量浓度范围内线性关系良好,相关系数(r2)均大于0.999,检出限(LOD)和定量下限(LOQ)分别为…查看全部>>
The method for the determination of 25 imidazole veterinary drugs and their metabolites in eggs was established by high performance liquid chromatography(HPLC).The egg solution was ex-tracted and concentrated by acetonitrile,purified by Oasis PRIME HLB solid phase extraction col-umn.The samples were eluted by gradient with methanol and water as mobile phases,separated by ZORBAX SB-Aq(250 mm×4.6 mm,5 μm)column,detected by diode array detector(DAD),and quantif…查看全部>>
邱月;余秋玲;谭超兰;陆嘉莉;杨倩
重庆市计量质量检测研究院,重庆 401123重庆市计量质量检测研究院,重庆 401123重庆市计量质量检测研究院,重庆 401123重庆市计量质量检测研究院,重庆 401123重庆市计量质量检测研究院,重庆 401123
化学
苯并咪唑硝基咪唑代谢物高效液相色谱法鸡蛋
benzimidazolenitroimidazolemetabolitehigh performance liquid chromatographyegg
《分析测试学报》 2024 (7)
1018-1024,7
重庆市科技局科研院所绩效激励引导专项(cstc2022jxjl50001)国家市场监督管理总局科技计划项目(2023MK106)重庆市市场监督管理局科研计划项目(CQSJKJ2022040,CQSJKJDW2023003)
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