高等学校化学学报2024，Vol.45Issue(7)：173-182,10.DOI:10.7503/cjcu20240169
聚醚醚酮纤维负载氧化铋的压电效应对成骨细胞分化的刺激作用
Piezoelectric Effect of Polyether Ether Ketone Fibers Loaded with Bismuth Oxide Stimulating Osteogenic Differentiation
摘要
Abstract
Oxygen-vacancy bismuth oxide(BiO2‒x)with excellent piezoelectric property was prepared by ultrasonic peel method and loaded on polyether ether ketone(PEEK)fiber by using chlorogenic acid.A kind of rotator cuff patch material with piezoelectric effect was designed,and its effects on macrophage polarization and osteoblast behavior were studied.The results showed that after loading BiO2‒x,not only the surface properties(roughness,hydrophilicity,and surface energy,etc.)of PEEK fibers were obviously improved,but also the piezoelectric proper-ties were significantly enhanced(piezoelectric coefficient of 3.8 pC/N,output voltage of 0.97 V and output current of 575.6 μA).The patch material not only promoted the anti-inflammatory M2 macrophage polarization,but also promoted the adhesion,proliferation,and osteogenic differentiation of osteoblasts.The patch material has potential application for repairing rotator cuff tear.关键词
聚醚醚酮纤维/表面改性/压电性能/巨噬细胞极化/成骨细胞分化Key words
Polyether ether ketone fiber/Surface modification/Piezoelectric effect/Macrophage polarization/Osteoblast differentiation分类
化学引用本文复制引用
梁露娴,宋安琪,周扬,孙平,王德强,魏杰..聚醚醚酮纤维负载氧化铋的压电效应对成骨细胞分化的刺激作用[J].高等学校化学学报,2024,45(7):173-182,10.基金项目
国家自然科学基金(批准号:32171340)资助.Supported by the National Natural Science Foundation of China(No.32171340). （批准号:32171340）
