广西植物2024，Vol.44Issue(6)：1151-1158,8.DOI:10.11931/guihaia.gxzw202308076
红叶野桐叶中的木脂素类化合物
Lignans from the leaves of Mallotus paxii
摘要
Abstract
Mallotus paxii is a Euphorbiaceae plant belonging to the genus Mallotus Lour.This genus mainly distributes in tropical and subtropical Asia,and there are about 140 species in the world.There are 36 species in China,including 11 varieties,which mainly grow in Guangxi,Guangdong and Hainan.To study the compounds of Mallotus paxii,twelve lignans were isolated from the leaves of M.paxii by means of various column chromatographic techniques,including silica gel,ODS,Sephadex LH-20 and preparative RP-HPLC methods.The structures of the isolated lignans were determined on the basis of analyses of spectroscopic methods(1H-and 13C-NMR spectroscopy),high-resolution electrospray ionization mass spectrometry(HR-ESI-MS),and comparison of their spectroscopic data with previously reported data.The lignans were identified as 7″,8″-threo-buddlenol D(1),buddlenol D(2),7″,8″-threo-buddlenol C(3),buddlenol C(4),(+)-syringaresinol(5),epipinoresinol(6),pinoresinol(7),1-acetoxyl-2e,6e-dipiperonyl-3,7-dioxabicyclo-[3,3,0]-octane(8),ciwujiatone(9),lariciresinol-4′-O-β-D-glucopyranoside(10),rel-(2α,3β)-7-O-methylcedrusin(11),and dihydrodehydrodiconiferyl-alcohol 4′-O-β-D-glucoside(12).All compounds were isolated from M.paxii for the first time.Some lignans have good pharmacological activities such as antibacterial,anti-inflammatory,anti-tumor and anti-virus.The results of this study show that the leaves of M.paxii are rich in lignans with good activity,indicating that its good medicinal value may be related to these lignans.关键词
野桐属/红叶野桐/(+)-丁香脂素/刺五加酮/松脂素Key words
Mallotus/Mallotus paxii/(+)-syringaresinol/ciwujiatone/pinoresinol分类
生物学引用本文复制引用
侯萍,任晨阳,黄艳,潘立卫,彭柳亭,甘纯秋,李俊..红叶野桐叶中的木脂素类化合物[J].广西植物,2024,44(6):1151-1158,8.基金项目
国家自然科学基金(32060097). （32060097）
