老年患者静脉血栓栓塞症的预防OACSTPCD
Prevention of venous thromboembolism in elderly patients
静脉血栓栓塞症(venous thromboembolism,VTE)是常见病,发病率和病死率高.在老年患者VTE发病率更高、病死率更高,年龄增加导致血栓标志物D-二聚体数值也增加,应用D-二聚体数值筛查VTE需要调整诊断阈值,年龄增加也是抗凝预防后出血的高危因素;另外,老年患者抗凝预防后仍有VTE发生;老年患者抗凝预防VTE是否需要监测,年龄与VTE复发关系尚无定论,深入研究老年预防VTE,并探索创新的VTE预防策略,是未来研究工作的方向.
Venous thromboembolism(VTE)is a common disease with high morbidity and mortality.The incidence and mortality of VTE are higher in elderly patients and increased level of D-dimer,a thrombosis marker is positively related with age.Therefore,the diagnostic threshold needs to be adjusted to screen VTE with D-dimer level.Elderly patients may still have VTE after implementation of anticoagulant prevention,and increasing age is a high risk factor for bleeding after anticoagulant prevention.Whether elderly patients need to be monitored for anticoagulant prevention of VTE,and the relationship between age and VTE recurrence remains to be determined.In-depth re-search on the prevention of VTE in elderly patients and exploration of innovative VTE prevention strategies may ori-ent future research.
丁梦希;王春梅
首都医科大学宣武医院全科医学科,北京 100053首都医科大学宣武医院重症医学科,北京 100053
临床医学
老年患者静脉血栓栓塞症预防
elderly patientvenous thromboembolismprevention
《基础医学与临床》 2024 (007)
916-920 / 5
首都卫生发展科研专项(首发 2022-2-2016)
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