脐带间充质干细胞输注对2型糖尿病合并非酒精性脂肪性肝病患者的疗效评估:一项前瞻性临床试验的事后分析OACSTPCD
Efficacy of UC-MSC infusion in patients with coexisting type 2 diabetes mellitus and nonalcoholic fatty liver disease:A post hoc analysis of a prospective clinical trial
背景 2型糖尿病(type 2 diabetes mellitus,T2DM)和非酒精性脂肪性肝病(nonalcoholic fatty liver disease,NAFLD)常并发,二者共患可加剧并发症及靶器官的损害.近年来国内外间充质干细胞治疗代谢病正在兴起,但其临床研究比较缺乏.目的 分析脐带来源的间充质干细胞(umbilical cord-derived mesenchymal stem cell,UC-MSC)对 T2DM和NAFLD…查看全部>>
Background Type 2 diabetes mellitus(T2DM)and nonalcoholic fatty liver disease(NAFLD)are often comorbid conditions,and their coexistence can exacerbate complications and damage target organs.In recent years,stem cell therapy for metabolic diseases using mesenchymal stem cell(MSC)has been emerging both domestically and internationally.However,clinical studies on their therapeutic effects are still sparse.Objective To investigate the therapeutic potential of um…查看全部>>
赵健;王岳鹏;侯禹;马旺田;母义明;谷伟军
解放军医学院,北京 100853||解放军总医院第一医学中心内分泌科,北京 100853解放军总医院第一医学中心内分泌科,北京 100853||南开大学医学院,天津 300071解放军医学院,北京 100853||解放军总医院第一医学中心内分泌科,北京 100853解放军总医院第一医学中心内分泌科,北京 100853解放军总医院第一医学中心内分泌科,北京 100853解放军总医院第一医学中心内分泌科,北京 100853
临床医学
2型糖尿病非酒精性脂肪性肝病脐带间充质干细胞胰岛素抵抗脂质代谢
type 2 diabetes mellitusnonalcoholic fatty liver diseaseumbilical cord-derived mesenchymal stem cellinsulin resistancelipid metabolism
《解放军医学院学报》 2024 (6)
571-577,583,8
北京市自然科学基金项目(7232155)
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