昆明医科大学学报2024，Vol.45Issue(7)：126-131,6.DOI:10.12259/j.issn.2095-610X.S20240719
血清25-羟基维生素D、钙、锌水平与儿童生长发育的关系
Relationship between Levels of Serum 25-hydroxyvitamin D,Calcium,Zinc and Growth and Development of Children
摘要
Abstract
Objective To observe the levels of serum 25-hydroxyvitamin D,calcium and zinc in children,and explore the relationship between the three indexes and the growth and development of children.Methods From January 2021 to December 2022,98 children with growth retardation treated in Zigong Maternal and Child Health Hospital were included in the growth retardation group,and 80 children with normal growth and development were taken as the normal growth and development group.The serum 25-hydroxyvitamin D,calcium,zinc level and other clinical data of the two groups were compared,and the relationship between serum 25-hydroxyvitamin D,calcium,zinc level and growth and development was analyzed.Results The levels of body length/height,weight,calcium,zinc and 25-hydroxyvitamin D in the growth retardation group were lower than those in the normal growth development group(P<0.05).The results of point-and-column correlation analysis showed that the levels of calcium,zinc and 25-hydroxyvitamin D were negatively correlated with children's growth retardation(r<0,P<0.05).Logistic regression model was established.The results showed that the levels of Size/height(95%CI:0.673～0.824),weight(95%CI:0.477～0.717),calcium(95%CI:0.127～0.467),zinc(95%CI:0.140～0.571)and 25-hydroxyvitamin D(95%CI:0.130～0.461)were the protective factors for children's growth and development(or<1 The ROC curve was drawn.The results showed that the levels of calcium,zinc and 25-hydroxyvitamin D had certain predictive value for children's growth and development(AUC=0.601,0.627 and 0.667),and the predictive value of The three indicators are parallel was higher(AUC=0.808).Conclusion The growth and development of children is closely related to the level of serum 25-hydroxyvitamin D,calcium and zinc.Clinical monitoring of the level of serum 25-hydroxyvitamin D,calcium and zinc is helpful for early prediction of children's growth and development.关键词
儿童/25-羟基维生素D/钙/锌/生长发育Key words
Children/25-hydroxyvitamin D/Calcium/Zinc/Growth and development分类
临床医学引用本文复制引用
张愉愉,卢游,刘宇..血清25-羟基维生素D、钙、锌水平与儿童生长发育的关系[J].昆明医科大学学报,2024,45(7):126-131,6.基金项目
四川省医学(青年创新)科研课题基金资助项目(Q20016) （青年创新）
