昆明医科大学学报2024，Vol.45Issue(7)：148-153,6.DOI:10.12259/j.issn.2095-610X.S20240722
高场强MRIT1灌注成像联合DWI成像在评估乳腺癌新辅助化疗疗效中的价值
Value of High Field Tntensity MRIT1 Perfusion Imaging Combined with DWI Imaging in Evaluating The Efficacy of Neoadjuvant Chemotherapy for Breast Cancer
摘要
Abstract
Objective To assess the potential value of high-field MRI T1 perfusion imaging combined with diffusion-weighted imaging(DWI)in evaluating neoadjuvant chemotherapy efficacy in breast cancer.Methods The clinical and radiological data,including pre-and post-chemotherapy T1 perfusion imaging and DWI imaging data,were retrospectively collected from 126 breast cancer patients.Multifactorial logistic regression analysis was used to investigate the relationship between different imaging parameters and neoadjuvant chemotherapy efficacy,and a predictive model was established.Results T1 perfusion parameters and DWI imaging parameters(area under the curve,time to peak,washing,maxenh,ADC value)were all related factors in evaluating the efficacy of neoadjuvant chemotherapy for breast cancer(P<0.05).The multifactorial logistic regression model based on these correlated parameters achieved an accuracy of 91.3%in predicting chemotherapy efficacy.Conclusions MRI T1 perfusion imaging combined with DWI imaging holds potential clinical application prospects in assessing neoadjuvant chemotherapy efficacy in breast cancer.Comprehensive analysis of MRI T1 perfusion imaging combined with DWI imaging parameters allows for a more accurate prediction of breast cancer patients'response to treatment,providing robust support for treatment decisions.关键词
磁共振灌注成像/扩散加权成像/乳腺癌/新辅助化疗Key words
Magnetic resonance perfusion imaging/Diffusion-weighted imaging/Breast cancer/Neoadjuvant chemotherapy分类
临床医学引用本文复制引用
张正,杨艳红,冯再辉,詹路江,普金仙,段茜婷..高场强MRIT1灌注成像联合DWI成像在评估乳腺癌新辅助化疗疗效中的价值[J].昆明医科大学学报,2024,45(7):148-153,6.基金项目
楚雄医药高等专科学校科研基金资助项目(2023YYXM14) （2023YYXM14）
