高场强MRIT1灌注成像联合DWI成像在评估乳腺癌新辅助化疗疗效中的价值OACSTPCD

Objective To assess the potential value of high-field MRI T1 perfusion imaging combined with diffusion-weighted imaging(DWI)in evaluating neoadjuvant chemotherapy efficacy in breast cancer.Methods The clinical and radiological data,including pre-and post-chemotherapy T1 perfusion imaging and DWI imaging data,were retrospectively collected from 126 breast cancer patients.Multifactorial logistic regression analysis was used to investigate the relationship between different imaging parameters and neoadjuvant chemotherapy efficacy,and a predictive model was established.Results T1 perfusion parameters and DWI imaging parameters(area under the curve,time to peak,washing,maxenh,ADC value)were all related factors in evaluating the efficacy of neoadjuvant chemotherapy for breast cancer(P<0.05).The multifactorial logistic regression model based on these correlated parameters achieved an accuracy of 91.3%in predicting chemotherapy efficacy.Conclusions MRI T1 perfusion imaging combined with DWI imaging holds potential clinical application prospects in assessing neoadjuvant chemotherapy efficacy in breast cancer.Comprehensive analysis of MRI T1 perfusion imaging combined with DWI imaging parameters allows for a more accurate prediction of breast cancer patients'response to treatment,providing robust support for treatment decisions.