This study was supported by the National Natural Scie-nce Foundation of China(No.82070432 & No.82070435 &No.82270469 & No.82370426),the Ministry of Science and Technology,Beijing,China(2018YFC1704902 & 2022YF-C3601302),the Shanghai Commissions of Science and Tec-hnology and Health(a special grant for"leading acade-mics")(No.19DZ2340200),and the Three-year Action Pr-ogram of Shanghai Municipality for Strengthening the Construction of Public Health System Big Data and Arti-ficial Intelligence Application,Shanghai,China(GWV-10.1-XK05).All authors had no conflicts of interest to dis-close except Dr.Wang reports receiving lecture and con-sulting fees from Novartis,Omron,and Viatris （No.82070432 & No.82070435 &No.82270469 & No.82370426）

and Dr.Li reports receiving research grants from A&D,Bayer,Omron,Salubris,and Shyndec and lecture fees from A&D,Novartis,Omron,Servier,Salubris and Shyndec.The authors gratefully acknowledge the voluntary partici-pation of the study participants from Yuyuan and Sanlin Communities,and the technical assistance of the physici-ans,nurses,technicians,and master and PhD students fr-om the Community Health Centres(Huangpu District and Pudong New Area,Shanghai)and the Shanghai Institu-te of Hypertension(Huangpu District,Shanghai). （Huangpu District and Pudong New Area,Shanghai）