南京医科大学学报（自然科学版）2024，Vol.44Issue(7)：979-984,6.DOI:10.7655/NYDXBNSN240242
肠道类器官基因编辑技术的研究进展
Research progress on gene-editing technology of intestinal organoids
摘要
Abstract
Intestinal organoid is a new experimental model and is widely used in research on intestinal diseases and functional changes for its property in mimicking structures and functions of in vivo organs.In recent years,researchers have combined gene-editing technology with intestinal organoids,offering possibilities for elucidating the mechanisms of diseases and developing targeted therapies for these diseases.This review looks back on the applications of gene-editing in intestinal organoids and their future perspectives in disease modeling and drug development.关键词
肠道类器官/干细胞/基因编辑Key words
intestinal organoids/stem cell/gene editing分类
生物科学引用本文复制引用
周寅,俞静,丁国宪..肠道类器官基因编辑技术的研究进展[J].南京医科大学学报（自然科学版）,2024,44(7):979-984,6.基金项目
国家重点研发计划(2022YFA0806100) （2022YFA0806100）
