摘要
Abstract
Objective:To explore and analyze the therapeutic effect of self-made blood stasis relipe plaster in patients with knee osteoarthritis and its influence on inflammatory factors.Methods:90 patients with knee osteoarthritis in our hospital were selected as the observation objects.The case selection and study time were from June 2020 to June 2022,and they were divided into control group,observation group and comfort group according to random number table method,with 30 patients in each group.Among them,the control group was treated with conventional therapy,the observation group was treated with self-made blood stasis relief plaster on the basis of conventional therapy,and the placebo group was treated with placebo.The clinical efficacy,complication rate,joint pain score,knee joint function score and inflammatory factors of the three groups were compared before and after treatment.Results:The excellent and good rate of clinical treatment in observation group 93.33% was higher than 83.33% in control group and comfort group 50.00%,and the the difference between the two groups were statistically significant(P<0.05).After treatment,the pain Visual Analogne Scale score of the observation group was lower than that of the control group and the comfort group,and the Hospital for Special Surgery score was higher than that of the control group and the comfort group,with statistical significance(P<0.05).The complication rate of the observation group 6.67% was lower than of the control group and the comfort group 26.67%,and the difference between the two groups were statistically significant(P<0.05).After treatment,the levels of serum inflammatory factors such as serun C-reactive protein,tumor necrosis factor-α,interleukin-1β,interleukin-6 and interleukin-8 in observation group were lower than those in control group and placebo group,with statistical significance(P<0.05).Conclusion:Self-made blood stasis relief plaster can play a significant role in the treatment of knee osteoarthritis patients,with good efficacy,which can help patients quickly relieve clinical symptoms and pain,promote the recovery of joint function,and also help improve inflammatory response and reduce the risk of complications.It is a safe and effective treatment.关键词
膝关节骨性关节炎/自制散瘀止痛贴膏/治疗效果/炎性因子Key words
Knee osteoarthritis/Self-made blood stasis plaster/Therapeutic effect/Inflammatory factor分类
医药卫生