中国伤残医学2024，Vol.32Issue(1)：53-57,5.DOI:10.13214/j.cnki.cjotadm.2024.001.013
VSD联合自体富血小板血浆凝胶在糖尿病慢性难愈合创面植皮治疗中的应用
Application of VSD Combined with Autologous Platelet-Rich Plasma Gel in Skin Grafting Treatment of Chronic Refractory Diabetic Wounds
摘要
Abstract
Objective:To analyze the application of continuous closed negative pressure drainage(VSD)combined with autologous platelet-rich plasma gel(APG)in skin grafting treatment of chronic refractory diabetic wounds.Methods:80 patients with chronic refractory diabetic wounds admitted to The third hospital of Inner Mongolia autonomous region from February 2021 to June 2022 were selected as the study objects.They were randomly divided into an observation group(n=37)and a control group(n=43).After debridement,the wound was covered by VSD in the control group.After debridement,APG was evenly applied on the wound in the observation group,and then VSD was applied to cover the wound.Skin grafting was performed when the wound of the two groups reached the condition of skin graft.Bacterial clearance before skin grafting,growth rate of granulation tissue before skin grafting,growth thickness of granulation tissue before skin grafting,wound healing rate,wound healing rate and curative effect indexes were compared between the two groups.Results:The bacterial clearance,growth rate of granulation tissue before skin grafting,growth thickness of granulation tissue before skin grafting,wound healing rate and wound healing rate of observation group were better than those of control group,and the difference was between the two groups statistically significant(P<0.05).The wound healing time of the observation group was shorter than that of the control group,and the total effective rate was higher,the difference was statistically significant(P<0.05).Conclusion:VSD combined with APG can effectively promote the growth of granulation tissue,shorten the time of wound healing,improve the healing quality of wound skin grafting and improve the therapeutic effect.关键词
糖尿病/慢性难愈合创面/VSD/APGKey words
Diabetes mellitus/Chronic refractory wound/VSD/APG分类
医药卫生引用本文复制引用
王鸿彬,程杰..VSD联合自体富血小板血浆凝胶在糖尿病慢性难愈合创面植皮治疗中的应用[J].中国伤残医学,2024,32(1):53-57,5.基金项目
内蒙古医科大学校百万课题(项目编号:YKD2018KJBW(LH)012) （项目编号:YKD2018KJBW(LH）
内蒙古自治区高等学校科学技术研究项目(项目编号:NJZY22673) （项目编号:NJZY22673）
