摘要
Abstract
Objective:To explore the value of magnetic resonance imaging(MRI)in the evaluation of microcirculation changes in patients with early steroid-induced osteonecrosis of the femoral head(SNFH).Methods:In this study,76 patients with suspected early steroid-induced osteonecrosis of the femoral head diagnosed and treated in our hospital from February 2019 to December 2022 were selected as the research objects.All patients were given magnetic resonance imaging examination,and the imaging characteristics and microcirculation changes were recorded to determine the diagnostic value.Results:Among the 76 patients,26 patients were pathologically diagnosed as early steroid-induced osteonecrosis of the femoral head(ONFH group)and 50 patients were pathologically diagnosed as hip osteoarthritis(OA group).The proportions of bone trabeculae blur,bone marrow edema,local cystic degeneration,and linear sign in the femoral head necrosis group were 80.8%,84.6%,92.3%,and 80.8%,respectively,which were higher than 12.0%,16.0%,50.0%,and 20.0%in the osteoarthritis group respectively,and the differences between the groups were statistically significant(P<0.05).The MRI microcirculation fat fraction and perfusion fraction in the osteonecrosis group were higher than those in the osteoarthritis group,and the difference between the groups was statistically significant(P<0.05).Twenty-five cases were diagnosed as early steroid-induced osteonecrosis of the femoral head by magnetic resonance imaging.The sensitivity and specificity of MRI in the differential diagnosis of early steroid-induced osteonecrosis of the femoral head were 96.2%and 100.0%,respectively.Receiver operating characteristic(ROC)curve analysis showed that the maximum area under the curve of MRI in the differential diagnosis of early steroid-induced osteonecrosis of the femoral head was 0.877.Conclusion:Patients with early steroid-induced osteonecrosis of the femoral head on MRI mostly show bone trabecula blur,bone marrow edema,local cystic degeneration,linear sign,accompanied by the increase of microcirculation fat fraction and perfusion fraction.Mri has high sensitivity and specificity in the diagnosis of early steroid-induced osteonecrosis of the femoral head.关键词
早期激素性股骨头坏死/MRI/骨髓水肿/微循环/脂肪分数/灌注分数Key words
Early steroid-induced osteonecrosis of the femoral head/Magnetic resonance imaging/Bone marrow edema/Microcirculation/Fat fraction/Fraction of perfusion分类
医药卫生
