老年股骨粗隆间骨折患者血清高密度脂蛋白水平与深静脉血栓形成的相关性OA

Objective:To investigate the correlation between serum high density lipoprotein(HDL-C)level and deep vein thrombosis(DVT)in elderly patients with intertrochanteric fracture of femur.Methods:The data of 76 elderly patients with femoral intertrochanteric fracture treated in our hospital from September 2019 to September 2022 were retrospectively analysed,and were divided into DVT group(n=8)and non-DVT group(n=68)according to whether DVT occurred.X-ray venography was performed in all patients 1 month after operation to determine the occurrence of DVT.HDL-C levels were detected in all patients 2 days after surgery and correlation analysis was performed.The two groups were compared with hemorheological indicators,four coagulation indicators,patients'basic conditions and surgery related indicators.Results:The HDL-C level in DVT group was lower than that in non-DVT group,and the D-dimer was higher than that in non-DVT group,with statistical significance(P<0.05).The fibrinogen in DVT group was higher than that in non-DVT group,and the difference was statistically significant(P<0.05).Spearman correlation analysis showed that HDL-C,D-dimer and fibrinogen were correlated with DVT(P<0.05).Unconditional Logistic regression showed that HDL-C,D-dimer and fibrinogen were important factors leading to DVT(P<0.05).Conclusion:The incidence of DVT is higher in elderly patients with intertrochanteric fracture after operation,which is often accompanied by decreased HDL-C level,abnormal hemorheology and coagulation function.HDL-C level in elderly patients with intertrochanteric fracture of femur is correlated with DVT.