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低分子肝素钙在股骨粗隆间骨折内固定患者中的应用

陈懋球 洪诗鹏 李泉森

中国伤残医学2024,Vol.32Issue(7):21-25,5.
中国伤残医学2024,Vol.32Issue(7):21-25,5.DOI:10.13214/j.cnki.cjotadm.2024.007.006

低分子肝素钙在股骨粗隆间骨折内固定患者中的应用

Application of Low Molecular Weight Heparin Calcium in Internal Fixation for Patients with Intertrochanteric Fractures of the Femur

陈懋球 1洪诗鹏 1李泉森1

作者信息

  • 1. 广东省封开县人民医院骨外科,广东 封开 526500
  • 折叠

摘要

Abstract

Objective:To explore the effect of using low molecular weight heparin calcium in internal fixation surgery for patients with intertrochanteric fractures of the femur.Methods:76 patients with intertrochanteric fractures of the femur admitted to our hospital from January 2021 to October 2022 were selected as the research subjects,divide them into a control group and a research group using a random number table method,with 38 cases.Both groups of patients underwent internal fixation surgery.The control group received pneumatic therapy,while the study group received low molecular weight heparin calcium therapy.Both groups received continuous treatment for 7 days.The clinical efficacy,coagulation function indicators,venous blood flow velocity,lower limb circumference,surgical time,intraoperative bleeding volume,total bleeding volume,occult blood loss,incidence of lower limb venous thrombosis,and incidence of adverse reactions between two groups were compared.Results:The total effective rate of the research group is higher than that of the control group,the difference was statistically significant(P<0.05).7 days after surgery,the PT and APTT in the research group were longer than those in the control group,and the D-D level was lower than that in the control group,the differences were statistically significant between the groups(P<0.05).7 days after surgery,the venous blood flow velocity in the research group was higher than that in the control group,and the circumference of the lower limbs was smaller than that in the control group,the differences were statistically significant between the groups(P<0.05).The incidence of lower limb venous thrombosis in the research group was lower than that in the control group,the difference was statistically significant(P<0.05).No serious adverse reactions were observed in both groups.Conclusion:The application of low molecular weight heparin calcium in internal fixation surgery for intertrochanteric fractures of the femur can improve the patient's coagulation function,accelerate venous blood flow,and prevent the occurrence of lower limb venous thrombosis.Moreover,the patient has a lower risk of bleeding and higher medication safety,which can be promoted and applied in clinical practice.

关键词

股骨粗隆间骨折/低分子肝素钙/股骨近端防旋髓内钉内固定/凝血功能/下肢静脉血栓

Key words

Intertrochanteric fractures of the femur/Low molecular weight heparin calcium/Proximal femoral nail anti-rotation internal fixation/Coagulation function/Lower limb venous thrombosis

分类

医药卫生

引用本文复制引用

陈懋球,洪诗鹏,李泉森..低分子肝素钙在股骨粗隆间骨折内固定患者中的应用[J].中国伤残医学,2024,32(7):21-25,5.

中国伤残医学

1673-6567

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