摘要
Abstract
Objective:To investigate the incidence of osteoporosis in patients with type 2 diabetes and analyze the risk factors,so as to provide clinical basis for preventing and controlling the occurrence and development of diabetic osteoporosis.Methods:77 patients with type 2 diabetes admitted to our hospital from March 2021 to April 2023 were selected as research objects,bone mineral density of all patients was detected and the incidence of osteoporosis was determined,general information and biochemical detection data of patients were investigated and recorded,and risk factors were analyzed.Results:Among the 77 patients,15 cases were judged to be osteoporosis(osteoporosis group),accounting for 19.5%.Bone mineral density(BMD)of the left hip joint,femoral neck,and the 1st to 4th lumbar vertebra in the osteoporosis group was lower than that of the non-osteoporosis group,and the differences were statistically significant(P<0.05).There were no significant differences in gender,body mass index and years of education between the two groups(P>0.05).There were significant differences in age and diabetes course between the two groups(P<0.05).The levels of serum total cholesterol,glycated hemoglobin,alkaline phosphatase and fasting blood glucose in osteoporosis group were higher than those in non-osteoporosis group,with statistical significance(P<0.05).There was no significant difference in triglyceride,low density lipoprotein cholesterol and high density lipoprotein cholesterol between the two groups(P>0.05).Spearman analysis showed that age,diabetes course,total cholesterol,glycated hemoglobin,alkaline phosphatase,fasting blood glucose were correlated with the occurrence of osteoporosis(P<0.05).Multivariate Logistic regression analysis showed that age,diabetes course,total cholesterol,glycosylated hemoglobin,alkaline phosphatase and fasting blood glucose were all risk factors for osteoporosis(P<0.05).Conclusion:Most patients with type 2 diabetes are complicated with osteoporosis.Age,diabetes course,total cholesterol,glycated hemoglobin,alkaline phosphatase and fasting blood glucose are all risk factors leading to osteoporosis,and targeted prevention and management should be carried out in clinic.关键词
2型糖尿病/骨质疏松/危险因素/总胆固醇/碱性磷酸酶/相关性分析Key words
Type 2 diabetes/Osteoporosis/Risk factors/Total cholesterol/Alkaline phosphatase/Correlation analysis分类
医药卫生
