四川中医2024，Vol.42Issue(6)：170-173,4.
柴胡疏肝散联合阶梯针刺法对气滯血瘀型带状疱疹后遗神经痛患者的影响
Effects of stepped acupuncture combined with Chaihu Shugan Powder on patients with postherpetic neuralgia of Qi stagnation and blood stasis type
摘要
Abstract
Objective To investigate the effects of step acupuncture combined with Chaihu Shugan Powder on present pain in-tensity(PPI)score,T lymphocyte subgroup levels in peripheral blood and sleep quality in patients with postherpetic neuralgia.Methods Ninety-six patients with herpes zoster postherpetic neuralgia of Qi stagnation and blood stasis type who were treated in our hospital(August 2018-August 2021)were randomly divided into acupuncture group(48cases)and combination group(48cases)by random number table.The acupuncture group was treated with step acupuncture,and the combination group was treated with Chaihu Shugan Powder combined with step acupuncture.The levels of pain substances[substance P(SP),neu-ropeptide Y(NPY),β-endorphin(β-EP)],the levels of peripheral blood T lymphocyte subsets(CD3+,CD4+,CD8+,CD4+/CD8+),the PPI score,and sleep quality[Athens Insomnia Scale(AIS)]before treatment and 7d,14d,20d after treat-ment were compared between the two groups.Results:The levels of SP,NPY and CD8+in the two groups were lower after treat-ment than before treatment(P＜0.05),and the levels of SP,NPY and CD8+in the combined group after treatment were lower than those in the acupuncture group(P＜0.05);the levels of β-EP,CD3+,CD4+,CD4+/CD8+in the two groups were higher after treatment(P＜0.05),and the combined group were higher than the acupuncture group(P＜0.05);the PPI and AIS scores of the two groups gradually decreased at 7d,14d,and 20d after treatment,and the PPI and AIS scores of the combined group were lower than the acupuncture group at 7d,14d,and 20d after treatment(P＜0.05).The total effective rate of the combined group(87.50％)was significantly higher than that of the acupuncture group(68.75％)(P＜0.05).Conclusion:Chaihu Shugan Powder combined with step acupuncture can reduce the pain degree of patients with postherpetic neuralgia of Qi stagnation and blood stasis type,improve cellular immune function and promote nerve function repair.关键词
柴胡疏肝散/阶梯针刺法/带状疱疹后遗神经痛,气滞血瘀型/睡眠质量/现有疼痛强度评分Key words
Chaihu Shugan Powder/step acupuncture/postherpetic neuralgia,Qi stagnation and blood stasis type/sleep quality/present pain intensity score分类
医药卫生引用本文复制引用
郭慧敏,李燕妮,刘波,古竹霞..柴胡疏肝散联合阶梯针刺法对气滯血瘀型带状疱疹后遗神经痛患者的影响[J].四川中医,2024,42(6):170-173,4.基金项目
陕西省自然科学基础研究计划项目(编号:2021JM-564) （编号:2021JM-564）
陕西省重点研发计划项目(编号:2018ZDXM-SF-010). （编号:2018ZDXM-SF-010）
