药学研究2024，Vol.43Issue(6)：549-553,5.DOI:10.13506/j.cnki.jpr.2024.06.005
不同发育时期忍冬花酚酸类成分含量变化
The phenolic acid content in flowers of Lonicera japonica Thunb.at different developmental stages
摘要
Abstract
Objective To compare the phenolic acid content in flowers of Lonicera japonica Thunb.at various developmental stages and evaluate the medicinal value of these flowers,this study aims to providing a reference for determining the optimal harvest period.Methods HPLC-ESI-MS/MS was used to determine the contents of 12 phenolic acids.The differences in phenolic acid composition in flowers of Lonicera japonica Thunb.at different developmental stages were compared using multivariate statistical analysis.Results The total phenolic acid contents in flowers of Lonicera japonica Thunb.were ranked from highest to lowest as follows:erbai stage>sanqing stage>dabai stage>milei stage>yinhua stage>jinhua flower stage.Conclusion The contents of phenolic acids in flowers of Lonicera japonica Thunb.at different developmental stages showed significant differences.The contents of protocatechuic acid and chlorogenic acid methyl ester were higher in open flowers,indicating that open flowers have unique developmental and utilization value.关键词
忍冬花/金银花/酚酸类成分/高效液相色谱电喷雾串联质谱/多元统计Key words
Flowers of Lonicera japonica Thunb./Lonicera japonica Thunb./Phenolic acids/HPLC-ESI-MS/MS/Multivariate statistical分类
中医学引用本文复制引用
王爱媛,范李想,张紫瑄,姚丹阳,张永清..不同发育时期忍冬花酚酸类成分含量变化[J].药学研究,2024,43(6):549-553,5.基金项目
国家重点研发计划项目(No.2017YFC1701503) （No.2017YFC1701503）
山东省自然科学基金项目(No.ZR2021QH238) （No.ZR2021QH238）
山东省医药卫生科技项目(No.202313051720) （No.202313051720）
