药学研究2024,Vol.43Issue(6):579-585,604,8.DOI:10.13506/j.cnki.jpr.2024.06.011
作用于肺癌多药耐药的中药单体化合物研究进展
Research progress on Chinese materia medica monomers acting on multidrug resistance in lung cancer
摘要
Abstract
Traditional Chinese medicine plays an active role in reversing drug resistance of lung cancer,and monomer compounds extracted from traditional Chinese medicine often have a good role.In order to review the research progress on TCM monomer compounds acting on multidrug resistance in lung cancer,TCM monomer,lung cancer and drug resistance were used as keywords to search the related literature in the databases of PubMed,Web of Science,CNKI,VIP,and Wanfang,etc.The relevant TCM monomer compounds,such as alkaloids,terpenoids,flavonoids,saponins and other compounds were summarized.The effects and mechanisms of these compounds in reversing lung cancer drug resistance were reviewed.It will provide reference and new ideas for the further research of these compounds.关键词
中药单体/肺癌耐药/作用机制/逆转耐药Key words
TCM monomer/Lung cancer drug resistance/Action mechanism/Reverse drug resistance分类
医药卫生引用本文复制引用
陆梅,张金杰,孙杉杉,吕光耀,吕文文,高新富..作用于肺癌多药耐药的中药单体化合物研究进展[J].药学研究,2024,43(6):579-585,604,8.基金项目
国家自然科学基金青年基金(No.81502937) (No.81502937)
山东省自然科学基金(No.ZR2018BH026) (No.ZR2018BH026)
滨州医学院科研启动基金(No.BY2016KYQD20) (No.BY2016KYQD20)
吴阶平医学基金(No.320.6750.2021-10-18) (No.320.6750.2021-10-18)
齐鲁卫生与健康杰出青年人才项目(No.鲁卫人才字[2020]3号) (No.鲁卫人才字[2020]3号)