药学研究2024，Vol.43Issue(6)：586-593,8.DOI:10.13506/j.cnki.jpr.2024.06.012
冰片"引药上行"作用及剂型研究进展
Research progress on the ″guiding drug up″effect and dosage forms of Borneol
摘要
Abstract
Borneol has a wide range of pharmacological effects in the treatment of cardiovascular and cerebrovascular diseases due to its heat-clearing and painkilling effects.At the same time,as a"drug priming",it promotes the penetration of other drugs through the blood-brain barrier by"aromatic opening the orifice and guiding drug up"and has been widely used in the design of brain-targeted drug delivery systems.Based on this,based on the pharmacological effects of Borneol,this paper focuses on the"guiding drug up"effect related mechanism of Borneol and its application in traditional compound dosage forms and modern nano-drug delivery systems.It aims to comprehensively reflect the overall progress of Borneol in the research field of"guiding drug",so as to provide a scientific reference for further exploring the medicinal value of Borneol and its modern application development research.关键词
冰片/引药上行/血脑屏障/脑靶向给药系统Key words
Borneol/Guiding drug up/Blood-brain barrier/Brain targeted drug delivery system分类
医药卫生引用本文复制引用
程红艳,陶稳稳,陶文康,张艳春,张彩云..冰片"引药上行"作用及剂型研究进展[J].药学研究,2024,43(6):586-593,8.基金项目
安徽省教育厅基金项目(No.KJ2021ZD0065) （No.KJ2021ZD0065）
安徽省科技重大专项项目(No.202203a07020031) （No.202203a07020031）
大学生创新创业训练计划项目(No.202110369021、202210369022) （No.202110369021、202210369022）
