实用妇产科杂志2024，Vol.40Issue(6)：486-489,4.
104例产前死胎原因的临床分析与探讨
Clinical Analysis and Discussion on the Causes of 104 Cases of Prenatal Still-birth
王链链 1杨玲 1顾宁 1柳华 1王志群 1戴毅敏1
作者信息
- 1. 南京大学医学院附属鼓楼医院妇产科,江苏 南京 210008
- 折叠
摘要
Abstract
Objective:The clinical data of prenatal stillbirth were analyzed in order to increase the understand-ing of the causes of stillbirth.Methods:Prenatal stillbirth cases that terminated pregnancy in Nanjing Drum Tower Hospital,Affiliated Hospital of Medical School,Nanjing University from January 2018 to December 2022 were col-lected,and the distribution characteristics of clinical data and the stillbirth causes were analyzed.The causes of death were classified according to the standards developed by the Stillbirth Collaborative Research Network(SCRN)in the United States,and they were divided into clear cause-of-death group and unknown cause-of-death group.The different characteristics of the two groups were compared and analyzed.Results:There were 210 ca-ses of prenatal stillbirth during the study period,and 104 cases met the inclusion criteria.Among them,33 cases(31.7%)had autopsy results,39 cases(37.5%)had genetic results,and 75 cases(72.1%)had placental pathol-ogy.According to the classification of SCRN standard,55 cases(52.9%)were probably related to the cause of death,33 cases(31.7%)were classified as possible,13 cases(12.5%)were probably unrelated,and 3 cases(2.9%)could not be attributed to the cause of death,that is,84.6%(88 cases)in the clear cause of death group and 15.4%(16 cases)in the unknown cause of death group.The rate of placental pathological examination in the clear cause of death group was significantly higher than that in the unknown cause of death group(78.4%).In the classification of causes of death,placental pathological changes accounted for the largest proportion,account-ing for 26.9%(28 cases),followed by pregnancy complications accounting for 25.0%(26 cases),and 15.4%of the cases were still unexplained.Conclusions:Placental pathology is of great significance for clarifying the cause of stillbirth.It is feasible to use SCRN to classify the etiology of stillbirth.Pathological placental conditions account for a relatively high proportion in the classification of stillbirth causes.It is recommended that each case of stillbirth placenta should undergo pathological examination.关键词
死胎/死胎原因/尸检/遗传学诊断/胎盘病理学Key words
Stillbirth/Cause of stillbirth/Autopsy/Genetic diagnosis/Placental pathology分类
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王链链,杨玲,顾宁,柳华,王志群,戴毅敏..104例产前死胎原因的临床分析与探讨[J].实用妇产科杂志,2024,40(6):486-489,4.
