实用医学杂志2024，Vol.40Issue(14)：1947-1951,5.DOI:10.3969/j.issn.1006-5725.2024.14.008
中老年居民动脉硬化自我筛查与基层医疗机构初筛工具构建
Self-screening for arteriosclerosis in middle-aged and elderly residents and the construction of a primary care initial screening tool
摘要
Abstract
Objective To establish a simple model for arteriosclerosis(AS)screening to provide a viable tool for the timely identification of AS risk among residents aged 40～65 years.Methods Data were obtained from the Sleep and Chronic Diseases Program in Fuquan City.The original dataset was divided into a training subset and a validation subset(80%:20%).LASSO and logistic regression models were used to screen variables,perform multivariate regression analyses.Internal validation was performed using the Bootstrap method.Nomogram Plot was constructed,and risk score thresholds were determined based on ROC curves to classify high-risk populations.Results RS Model was established to include age,gender,napping,sleep efficiency,sleep disorders,hyperten-sion and diabetes,with AUC=74.80%and a model risk score threshold=84.20.PHC Model was established to include age,gender,napping,sleep efficiency,systolic blood pressure,fasting blood glucose,and pulse variables,with AUC=82.80%and a risk score threshold of 78.00.Decision curves showed that both models performed well in terms of calibration and actual benefits for health management.Conclusion The two AS screening models exhibit acceptable accuracy and differentiation.Therefore,it can be applied in residents'self-health management and in primary care organizations'screening work in a large scale.关键词
动脉硬化/筛检模型/中老年人/列线图/基层医疗机构Key words
arteriosclerosis/screening model/middle-aged adults/nomogram graph/primary care organization分类
医药卫生引用本文复制引用
蒙玥,郑利,周静,王大珊,胡瑾,汪蝶,李游,汪俊华,王子云..中老年居民动脉硬化自我筛查与基层医疗机构初筛工具构建[J].实用医学杂志,2024,40(14):1947-1951,5.基金项目
国家自然科学基金项目(编号:81960612) （编号:81960612）
贵州省科技计划项目(编号:黔科合基础-ZK[2022]一般382) （编号:黔科合基础-ZK[2022]一般382）
