天津中医药2024，Vol.41Issue(7)：945-952,8.DOI:10.11656/j.issn.1672-1519.2024.07.24
微生物-肠-脑轴视域下认知障碍的发病机制及中医药治疗进展
Exploring the pathogenesis of cognitive impairment from the perspective of microbiota-gut-brain axis and advances in traditional Chinese medicine treatment
摘要
Abstract
Cognitive impairment has become a common disorder affecting the health of the elderly population,and there is still a lack of effective treatments.The microbiota-gut-brain axis(MGBA)provides a new perspective for understanding cognitive disorders and a new direction for future clinical diagnosis and treatment of cognitive disorders.Therefore,this paper discusses the role of MGBA in the pathogenesis of cognitive disorders from the perspective of MGBA,and also summarizes the latest research progress in traditional Chinese medicine for the treatment of cognitive disorders in this perspective.The results show that MGBA can affect the development of cognitive disorders through immune,neural and endocrine pathways.At the same time,related herbal compounds,herbal monomers and acupuncture treatments have been shown to improve cognitive function by modulating MGBA,providing a better modern interpretation of TCM for the treatment of cognitive disorders.关键词
微生物-肠-脑轴/认知障碍/机制/中医药Key words
microbiota-gut-brain axis/cognitive impairment/pathogenesis/traditional Chinese medicine分类
医药卫生引用本文复制引用
于丽,苗蓓亮,刘学焕,刘筠..微生物-肠-脑轴视域下认知障碍的发病机制及中医药治疗进展[J].天津中医药,2024,41(7):945-952,8.基金项目
天津市自然科学基金面上项目(21JCYBJC00120) （21JCYBJC00120）
天津市卫生健康委员会中医、中西医结合重点项目(2021029). （2021029）
