现代医药卫生2024，Vol.40Issue(13)：2245-2248,4.DOI:10.3969/j.issn.1009-5519.2024.13.018
集束化护理对口服吡咯替尼片所致腹泻患者的干预效果
Intervention effect of cluster nursing in patients with diarrhea caused by oral pyrrotinib tablets
宋文婷 1阮寒光 1许莉 1胡丽群 1李红霞 1谌松霖1
作者信息
摘要
Abstract
Objective To explore the intervention effect of cluster nursing in patients with diarrhea caused by oral pyrrotinib tablets.Methods A total of 100 patients with advanced breast cancer admitted to the hospital from March 2022 to February 2023 were selected and divided into the control group and the obser-vation group according to random number table,with 50 patients in each group.Both groups were treated with pyrrotinib.The control group performed routine nursing care,and the observation group performed cluster nursing care.The grade of diarrhea degree,the improvement of diarrhea symptoms,medication compliance and the occurrence of adverse reactions were compared between the two groups.Both groups maintained continu-ous care for one week.Results The grade of diarrhea in the observation group was better than that of the con-trol group,and the difference was statistically significant(Z=-2.377,P=0.017).The number of diarrhea in the observation group was(4.01±0.98),which was less than that in the control group(6.69±1.20),and the diarrhea recovery time was(3.06±0.22)d,which was shorter than that in the control group(5.12±0.33)d,the differences were statistically significant(t=12.232,P＜0.001;t=36.727,P＜0.001).The medication compliance[96.00％(48/50)]in the observation group was higher than that in the control group[84.00％(42/50)],the incidence of adverse reactions in the observation group[6.00％(3/50)]was lower than that in the control group[22.00％(11/50)],and the differences were statistically significant(X2=4.000,P=0.046;X2=5.316,P=0.021).Conclusion Cluster nursing intervention measures have good application effects in patients with oral pyrrolitinib tablets,which is conducive to improving their medication compliance,reducing the sever-ity of diarrhea,which is beneficial for patient prognosis.关键词
乳腺癌/吡咯替尼/集束化护理/腹泻/有效性/安全性Key words
Breast cancer/Pyrrolitinib/Cluster nursing/Diarrhea/Validity/Security分类
医药卫生引用本文复制引用
宋文婷,阮寒光,许莉,胡丽群,李红霞,谌松霖..集束化护理对口服吡咯替尼片所致腹泻患者的干预效果[J].现代医药卫生,2024,40(13):2245-2248,4.
