新疆师范大学学报（自然科学版）2024，Vol.43Issue(4)：36-43,8.
健康与致病菌感染双峰驼肠道细菌和真菌群落的比较分析
Diversity Analysis of Intestinal Bacterial and Fungal Communities between Healthy and Infected Bactrian Camels
摘要
Abstract
High-throughput sequencing technique was used to analyze the diversity and structural composition of bacterial and fungal flora in fecal samples of four adult bactrian camels in Barkun County,Xinjiang,reflect the characteristics of intestinal flora infected by pathogenic bacteria and the relationship between intestinal flora imbalance and bactrian camel health and the gene function was predicted at the bacterial and fungi level.The results showed that there was no significant differences in the microbial community structure characteristics among CG.101,CG.103 and CG.104 samples(P＞0.05),for example,the largest taxonomic groups at the level of phylum,family and genus of bacterial community were Firmicutes,Ruminococcaceae and Bacteroides;The dominant phylum of fungi included Ascomycetes and Basidiomycetes.Compared with the above three samples,sample CG.102 had lower microbial diversity and relative abundance of beneficial bacteria,but more Conditional pathogens and pathogenic bacteria.At the Phylum level,sample CG.102 had lower abundance of Firmicutes and Bacteroides,and higher abundance of Proteobacteria and Actinobacteria.At the family level,the relative abundant of Akkermansia,Ruminococcaceae,Christensenellaceae,Rikenellaceae was significantly lower;At the genus level,the relative abundance of Akkermansia,Bacteroides,Ruminococcaceae and Bacillus was obviously lower than that of the other three samples;At the species level,a high proportion of Pseudomonas aeruginosa and Acithrobacter lwoffii were detected in sample CG.102.The fungal community of sample CG.102 was dominated by a single Ascomycota,Ascomycodaceae,Hyphomycetes,Scedosporium prolificans.The prediction of bacterial indicated that the camel represented by CG.102 sample have decreased immunity and be infected with diseases.关键词
高通量测序/粪便/菌群失衡/细菌多样性/真菌多样性Key words
High-throughput sequencing/Feces/Unbalanced flora/Bacterial diversity/Fungal diversity分类
生物科学引用本文复制引用
白茹,袁青青,张晓乐,吾尔恩·阿合别尔迪,木古丽·木哈西..健康与致病菌感染双峰驼肠道细菌和真菌群落的比较分析[J].新疆师范大学学报（自然科学版）,2024,43(4):36-43,8.基金项目
伊犁师范大学微生物资源保护与开发利用重点实验室项目(YLUKLM2018003). （YLUKLM2018003）
