中国当代儿科杂志2024，Vol.26Issue(7)：730-735,6.DOI:10.7499/j.issn.1008-8830.2402020
新生儿慢性肉芽肿病胸部计算机断层扫描的特征分析
Chest computed tomography manifestations in neonates with chronic granulomatous disease
摘要
Abstract
Objective To study chest computed tomography(CT)manifestations in neonates with chronic granulomatous disease(CGD)to provide clues for early diagnosis of this disease.Methods A retrospective analysis was conducted on the clinical data and chest CT scan results of neonates diagnosed with CGD from January 2015 to December 2022 at Anhui Provincial Children's Hospital.Results Nine neonates with CGD were included,with eight presenting respiratory symptoms as the initial sign.Chest CT findings included:consolidation in all 9 cases;nodules in all 9 cases,characterized by multiple,variably sized scattered nodules in both lungs;masses in 4 cases;cavities in 3 cases;abscesses in 6 cases;bronchial stenosis in 2 cases;pleural effusion,interstitial changes,and mediastinal lymphadenopathy each in 1 case.CT enhancement scans showed nodules and masses with uneven or ring-shaped enhancement;no signs of pulmonary emphysema,lung calcification,halo signs,crescent signs,bronchiectasis,or scar lesions were observed.There was no evidence of rib or vertebral bone destruction.Fungal infections were present in 8 of the 9 cases,including 6 with Aspergillus infections;three of these involved mixed infections with Aspergillus,with masses most commonly associated with mixed Aspergillus infections(3/4).Conclusions The primary manifestations of neonatal CGD on chest CT are consolidation,nodules,and/or masses,with Aspergillus as a common pathogen.These features can serve as early diagnostic clues for neonatal CGD.关键词
慢性肉芽肿/计算机断层扫描/曲霉菌/新生儿Key words
Chronic granulomatous disease/Computed tomography/Aspergillus/Neonate引用本文复制引用
疏恒,王丽丽,叶同生,林先红,毕少华,赵育弘,汪平生,戴立英..新生儿慢性肉芽肿病胸部计算机断层扫描的特征分析[J].中国当代儿科杂志,2024,26(7):730-735,6.基金项目
安徽省儿童医院优秀专科医师培养计划(eyrc32). （eyrc32）
