中国临床医学2024，Vol.31Issue(3)：470-476,7.DOI:10.12025/j.issn.1008-6358.2024.20230673
肾源性腺瘤临床病理特征分析
Analysis of the clinicopathological characteristics of nephrogenic adenoma
王玉豪 1盛文旭 2倪筝 1顾文怡 1黄玉凤 1闫会昌 3纪元1
作者信息
- 1. 复旦大学附属中山医院病理科,上海 200030
- 2. 山东省莱阳卫生学校病理生物教研室,烟台 265200
- 3. 河南科技大学第三附属医院皮肤科,洛阳 471000
- 折叠
摘要
Abstract
Objective To explore the clinicopathological and immunohistochemical features of nephrogenic adenoma(NA).Methods Clinical data of NA patients diagnosed in the Department of Pathology,Zhongshan Hospital,Fudan University from July 2016 to October 2022 were collected and analyzed to explore their clinicopathological features.Results A total of 13 NA cases were enrolled.There were 11 males and 2 females.Organs involved:ureter(n=7),bladder(n=5),bladder and ureter(n=1),renal pelvis(n=2).NA patients performed as ureteral stenosis(6/7),rough bladder wall(3/5),and renal pelvis polyp(2/2).The typical microscopical features of NA were tubular(13/13)and papillary(4/13)structures,covered with cuboidal or columnar epithelium(13/13),or a mixed hobnail-spike eosinophilic epithelium(12/13);the interstitium was loose,containing varied amounts of vasculature and inflammatory cells(13/13).Immunohistochemistry revealed specific expressions of CK7,PAX-8,CK19 and CK8.Conclusions NA is a rare neoplasm of the urinary system with unique histological features.NA has the risk of misdiagnosis and over-treatment,and the potential of recurrence and malignant conversion.The diagnosis of NA depends on pathology,and the immunohistochemistry can be helpful for its pathological diagnosis.关键词
肾源性腺瘤/临床病理特征/免疫组织化学Key words
nephrogenic adenoma/clinicopathological features/immunohistochemistry分类
医药卫生引用本文复制引用
王玉豪,盛文旭,倪筝,顾文怡,黄玉凤,闫会昌,纪元..肾源性腺瘤临床病理特征分析[J].中国临床医学,2024,31(3):470-476,7.
