中国临床医学2024，Vol.31Issue(3)：491-498,8.DOI:10.12025/j.issn.1008-6358.2024.20231914
早发冠心病发病机制与预防的研究进展
Research progress on pathogenesis and prevention of premature coronary heart disease
摘要
Abstract
The conventional risk factors associated with coronary heart disease(CHD)include hypertension,diabetes mellitus,dyslipidemia and hypercholesterolemia,obesity and overweight,smoking and alcohol consumption,etc..The incidence of CHD has increased year by year,and a discernible shift towards a younger age of onset is evident."The third report of the national cholesterol education program adult treatment panel Ⅲ"(NCEP ATP-Ⅲ)defines premature CHD(PCHD)as manifestation in males＜55 years and females＜65 years.At recently,PCHD has emerged as a focal point in both domestic and international study.In addition to the established risk factors,there is a important need to elucidate novel pathogenic mechanisms and predictive factors governing PCHD.This necessitates concerted efforts in primary prevention.This manuscript conducts a comprehensive review of antecedent researches,with the primary objective of discussing the latest pathogenic mechanisms and predictive factors associated with PCHD.The reviewing aim is to contribute substantive insights to the primary prevention of PCHD.关键词
早发冠心病/发病机制/一级预防/微血管功能/预测因素Key words
premature coronary heart disease/pathogenesis/primary prevention/microvascular function/predictive factor分类
医药卫生引用本文复制引用
张晏铭,于高修,王聪,陈峰..早发冠心病发病机制与预防的研究进展[J].中国临床医学,2024,31(3):491-498,8.基金项目
海军军医大学青年培育项目(2023QN061),海军军医大学第一附属医院青年培育项目(2021JCQN15).Supported by Youth Training Program of Naval Medical University(2023QN061)and Youth Training Program of The First Affiliated Hospital of Naval Medical University(2021JCQN15). （2023QN061）
