安徽大学学报（自然科学版）2024，Vol.48Issue(4)：80-89,10.DOI:10.3969/j.issn.1000-2162.2024.04.013
宽叶独行菜提取物微胶囊的制备与表征
Preparation and characterization of microcapsules of Lepidium latifolium L.extract
摘要
Abstract
Using microcapsule technology,microcapsules of extract of Lepidium latifolium L.have been prepared with the extract of L.latifolium L.as core material and sodium alginate as wall material.Response surface tests were designed and their properties were characterized.The results showed that the optimal plan for preparing microcapsules from the extract of L.latifolium L.was as follows:sodium alginate mass concentration was 2.0％,calcium chloride mass concentration was 2.0％,core-wall mass ratio was 1∶3,among which the concentration of sodium alginate was the most influential factor on microcapsules.It could be seen from SEM images that the microcapsules were spherical,regular in shape,compact in structure,and the microcapsules had good overall formability.FTIR and TG spectra also showed that the extract was well encapsulated in the wall material and had good thermal stability.Finally,the microcapsules were used to simulate digestion in vitro with intestinal fluid,and the release of microcapsules was 80.21％and 24.32％after 12 h in the cumulative intestinal fluid and gastric fluid,respectively.The kinetics of the release of microcapsules in gastrointestinal fluids was also fitted,and the results showed that the zero-order fitting equation better reflected the in vitro release behavior.关键词
宽叶独行菜提取物/锐孔造粒/海藻酸钠/微胶囊Key words
Lepidium latifolium L.extract/perforated granulation/sodium alginate/microcapsule分类
轻工纺织引用本文复制引用
张跃跃,乐政涛,于瑞涛,宋吉明..宽叶独行菜提取物微胶囊的制备与表征[J].安徽大学学报（自然科学版）,2024,48(4):80-89,10.基金项目
安徽省重点研究与开发立项项目(2022j11020012) （2022j11020012）
