安徽医科大学学报2024，Vol.59Issue(7)：1244-1250,7.DOI:10.19405/j.cnki.issn1000-1492.2024.07.021
疑似神经行为发育迟缓幼儿相关影响因素研究
Study on influencing factors of neurobehavioral development in young children suspected of developmental delays
摘要
Abstract
Objective To investigate the neurobehavioral development of young children aged 24 to 60 months in Shunde and explore the factors influencing the development of young children and provide reference for the interven-tion of neurobehavioral development delays in young children.Methods A retrospective cohort study was used to enroll the young children who were initially screened by the Pediatric Neuropsychological Developmental Scale(Pe-diatric Heart Scale)with a score of ≤85 was included in the study.With a score of ≤85,the young children might be at risk of developmental delays,and needed to be further diagnosed by the GESELL Developmental Diagnostic Scale,the basic information of the young children and their mothers at the time of birth were investigated,as well as basic information about the young children at the time of completing the GESELL Developmental Diagnostic Scale was collected.Results A total of 271 young children were included,196 males and 75 females.Young children had the lowest developmental quotient(DQ)in the language domain among the five domains(P＜0.001).Multiple lin-ear regression models showed:compared with girls,the language domain DQ of boys decreased by 5.321 points(P=0.049,95％CI:-10.620--0.021),and the personal-social domain DQ decreased by 4.474 points(P=0.023,95％CI:-8.316--0.631).Compared with young children via natural vaginal delivery(NVD),the gross motor domain DQ of young children via caesarean section(CS)decreased by 4.890 points(P=0.008,95％CI:-8.499--1.281),the fine motor domain DQ decreased by 3.373 points(P=0.037,95％CI:-6.532--0.213),the language domain DQ decreased by 7.621 points(P=0.004,95％CI:-12.826--2.416),per-sonal-social domain DQ decreased by 6.232 points(P=0.001,95％CI:-10.006--2.457).The results of bi-nary logistic regression models showed,compared with young children via NVD,the risk of gross motor domain retar-dation in young children increased(OR=1.763,95％CI:1.003-3.100),the risk of fine motor domain retardation increased(OR=2.217,95％CI:1.235-3.980),the risk of language domain retardation increased(OR=3.306,95％CI:1.080-10.124).Conclusion Young children with suspected neurobehavioral delays were more likely to have delayed development in language domain than in other domains,boys had lower DQ in language domain and personal-social domain than girls,and the development of young children via CS was slower than that via NVD.Fo-cus should be on the language development of young children especially on the language and personal-social devel-opment of boys.Carefully chose delivery way.Focus should be placed on assessment of young children's comprehen-sive neurobehavioral development in early time.关键词
幼儿/分娩方式/新生儿促甲状腺激素/神经行为发育/发育迟缓Key words
young children/delivery way/neonatal thyroid stimulating hormone/neurobehavioral development/de-layed development分类
医药卫生引用本文复制引用
李小嫚,杜进林,黄丽娟,王筱,刘祖民,郭润民,农雪艳,黄秀娟,朱锦渊,陈艳婷..疑似神经行为发育迟缓幼儿相关影响因素研究[J].安徽医科大学学报,2024,59(7):1244-1250,7.基金项目
广东省基础与应用基础研究联合基金(编号:2021A1515110545) （编号:2021A1515110545）
广东医科大学博士学位人员科研启动基金(编号:GDMUB2021001) （编号:GDMUB2021001）
