中医药临床杂志2024，Vol.36Issue(6)：1110-1119,10.DOI:10.16448/j.cjtcm.2024.0623
针药结合治疗溃疡性结肠炎疗效评价研究
Systematic Evaluation of Acupuncture Combined with Medicine in Treatment of Ulcerative Colitis
摘要
Abstract
Objective:To asess the efficacy and safety of acupuncture combined with western medicine in treatment of ulcerative colitis(UC).Method:The randomized controlled trials of combined acupuncture and medication for UC were collected,and the included literatures were stratified according to different treatment strategies.The quality of included literatures was evaluated by the Cochrane collaboration's bias risk assessment tool,and included literatures were systematically evaluated.Results:A total of 23 articles met the inclusion criteria.The results of meta-analysis suggested that the effective rate was the outcome index of the combined acupuncture and drug therapy group compared with the conventional treatment group,and the combined OR was 4.81,95％CI[3.63,6.37].Syndrome indicators of traditional Chinese medicine,abdominal pain,diarrhea,pus and blood stools were outcome indicators,and their combined SMD was-0.92,-1.93,-1.68,95％CI was[-1.34,-0.50],[-2.94,-0.92],[-2.67,-0.70],respectively.Geboes scale score was the outcome index,and its SMD was-3.09,95％CI[-8.06,1.89].Patient satisfaction was the outcome index,RR was 1.26,95％CI was[1.09,1.45].The outcome index was hospitalization expense,SMD was-9.93,95％CI[-11.83,-8.56].The outcome index was length of stay,and MD was-20.39,95％CI[-32.70,-8.07].All the indicators of the two groups were compared,except that there was no significant difference in the Geboes scale score,and all the other outcome indicators were statistically significant.Conclusion:The evaluation results of this system showed that the combination of acupuncture and drug therapy for UC could significantly improve the clinical ef-ficacy,significantly improve the clinical manifestations of abdominal pain,diarrhea,pus and blood stools,improve the satisfaction of patients,reduce the length of stay in hospital,reduce the cost of hospitalization,and no serious adverse reactions were observed,Therefore,acupuncture and medicine combination therapy is the best combination to treat this disease.Due to the relatively low quality of the included studies,more and higher quality studies are needed for further analysis.关键词
针药结合/溃疡性结肠炎/随机对照试验/系统评价/Meta分析Key words
combination of acupuncture with medicine/ulcerative colitis/randomized controlled trials/systematic review/meta analysis分类
医药卫生引用本文复制引用
张永跟,颜小飞,胡红昊,刘兰林,何明,李学军..针药结合治疗溃疡性结肠炎疗效评价研究[J].中医药临床杂志,2024,36(6):1110-1119,10.基金项目
安徽中医药大学博士后岗位人才项目(RD17100570) （RD17100570）
安徽省高等学校省级质量工程项目(2020jyxm1017) （2020jyxm1017）
安徽中医药大学校级纵向探索课题(2021zxts42) （2021zxts42）
安徽中医药大学校级教研课题(2019xjjy_yb008) （2019xjjy_yb008）
安徽省精品资源共享课资助项目(2012gxk063) （2012gxk063）
全国第四批中医优秀人才研修项目 （）
