中医药临床杂志2024，Vol.36Issue(6)：1139-1143,5.DOI:10.16448/j.cjtcm.2024.0628
半夏泻心汤联合四联疗法治疗慢性萎缩性胃炎癌前病变疗效分析
Analysis of the Therapeutic Effect of Banxia Xiexin Decoction Combined with Quadruple Therapy in the Treatment of Precancerous Lesions in Chronic Atrophic Gastritis
摘要
Abstract
Objective:To observe the clinical efficacy of Banxia Xiexin Decoction combined with Quadruple Therapy in the treatment of precancerous lesions in chronic atrophic gastritis.Method:160 patients with precancerous lesions of chronic atrophic gastritis from December 2020 to December 2023 admitted to the Dongba campus of Beijing First Tra-ditional Chinese and Western Medicine Hospital were randomly divided into two groups using a random number table method,with 80 cases in each group.The control group received quadruple therapy,while the observation group re-ceived treatment with Banxia Xiexin Decoction and Jiawei Decoction in addition to the control group.They were treated for 2 weeks,compare the clinical efficacy,traditional Chinese medicine syndrome score,pathological tissue score,gastrin-17(G-17),PG-Ⅰ and PG-Ⅱ.Result:After treatment,the total effective rate of the observation group was higher(P＜0.05).The TCM syndrome scores,pathological tissue score,PG-Ⅰ and PG-Ⅱ of both groups were lower than before treatment(P＜0.05),and the experimental group were lower(P＜0.05),both groups of G-17 levels were higher than before treatment(P＜0.05),while the experimental group was higher(P＜0.05),the Hp eradication rate in the experimental group was higher(P＜0.05).Conclusion:Banxia Xiexin Decoction can improve the treatment effect,and clinical symptoms,regulate the secretion of gastrin and pepsinogen,repair damaged gastric mucosal tissue,and help reverse pathological changes in gastritis,promote Hp to turn negative,it is worth promoting.关键词
慢性萎缩性胃炎/癌前病变/四联疗法/半夏泻心汤Key words
chronic atrophic gastritis/precancerous lesions/quadruple therapy/Banxia Xiexin Decoction分类
医药卫生引用本文复制引用
吕安定,杜囚鹏,景竹春..半夏泻心汤联合四联疗法治疗慢性萎缩性胃炎癌前病变疗效分析[J].中医药临床杂志,2024,36(6):1139-1143,5.基金项目
中国中医药研究促进会科研立项(2022063) （2022063）
