中医康复2024，Vol.1Issue(2)：23-27,5.DOI:10.19787/j.issn.2097-3128.2024.02.005
通督调神针法介入时机对急性脑梗死溶栓后神经功能的影响
The Effect of Timing of Tongdu Tiaoshen Acupunture Intervention on Neurological Function Following Thrombolysis in Acute Cerebral Infarction
摘要
Abstract
Objective Objective:To assess the impact of different timing interventions of Tongdu Tiaoshen Acupunture method on neurological function and levels of t-PA,PAI-1,and D-D in patients with hemiplegia following thrombolysis for acute cerebral infarction.Methods:SPSS25.0 software was em-ployed to establish baseline equivalence between groups.A total of 68 matched patients were divided into four groups,A,B,C,and D,according to the timing of acupunture intervention after thrombolysis.Group A(at the time of thrombolysis)consisted of 17 patients,group B(within 24 hours af-ter thrombolysis)consisted of 17 patients,group C(after 72 hours after thrombolysis)consisted of 17 patients,and group D(without acupuncture)consisted of 17 patients.All four groups received intravenous rt-PA thrombolysis and conventional treatment,while groups A,B,and C were treated with Tongdu Tiaoshen Acupunture method,once a day,for 14 days per treatment course,with continuous treatment for two courses.The treatment pe-riod was set at 28 days for all four groups,and patients were followed up until 90 days after the onset of the disease.The improvement of neurologi-cal function,daily living ability,and degree of disability at each time point before and after treatment were assessed in the four groups,and the changes in serum t-PA,PAI-1,and D-D levels were detected.Results:The improvement of NIHSS,BI,and mRS,as well as blood rheology,in groups A,B,and C were significantly better than those in group D(the control group),with groups A and B being better than group C.There was no significant difference between group A and group B.The timing of acupunture was independently associated with patients'neurological function,daily living ability,and disability status at 30 days of onset and living ability and disability status at 90 days(P＜0.05).Conclusion:The timing of acu-puncture intervention is an independent factor affecting the neurological function of the cerebral infarct limbs,daily living ability,and the degree of disability of patients.The efficacy acupuncture intervention within 24 hours following thrombolysis may be superior.and Tongdu Tiaoshen Acupun-ture can improve neurological function,blood rheology index,daily living ability,and reduce the disability rate in patients with higher safety.These results are worth promoting in clinical application.关键词
通督调神针法/脑梗死/阿替普酶/介入时机Key words
Tongdu Tiaoshen Acupunture/cerebral infarction/Alteplase/intervention timing分类
医药卫生引用本文复制引用
魏翠颖,马宇标,李新华..通督调神针法介入时机对急性脑梗死溶栓后神经功能的影响[J].中医康复,2024,1(2):23-27,5.基金项目
广州市卫生健康科技项目(2022A011026) （2022A011026）
