八段锦调节肠道菌群对帕金森病抑郁和便秘症状的治疗思路探讨OA

Depression and constipation are typical symptoms of Parkinson's disease in the early and prodromal stages,which seriously affect the qual-ity of life and disease progression of patients.As a traditional Chinese medicine technique,Baduanjin has a unified effect of regulating body,heart,and breath,and has a positive therapeutic effect on depression and constipation in Parkinson's disease.The functional changes of gut microbiota medi-ate the formation of depression and constipation symptoms in Parkinson's disease through the Neuroendocrine immune system pathway,and Baduan-jin has a positive impact on regulating the abundance of beneficial gut microbiota.Therefore,Parkinson's disease depression and constipation symp-toms,Baduanjin and gut microbiota,are closely related.Baduanjin can treat Parkinson's disease depression and constipation by regulating gut micro-biota.However,the relevant pathways and mechanisms are still unclear,and further research is needed to provide new treatment ideas for depression and constipation symptoms in Parkinson's disease.