KLF4在糖尿病肾脏病Ⅲ～Ⅳ期肾精亏虚证中的表达和临床意义OACSTPCD
Expression and clinical significance of KLF4 in stage Ⅲ-Ⅳ diabetic kidney disease(DKD)with kidney essence deficiency
目的 探讨尿液Krüppel样转录因子 4(krüppel-like factor 4,KLF4)在糖尿病肾脏病(diabetic kidney disease,DKD)中的表达和临床意义,探寻KLF4 与DKD肾精亏虚证的关联性.方法 纳入2022 年1 月至2023 年3 月期间就诊于北京中医药大学附属东直门医院的符合诊断标准的Ⅲ～Ⅳ期DKD患者45 例,2 型糖尿病(type 2 diabetes mellitus,T2DM)患者56 例及…查看全部>>
Objective To investigate the expression and clinical significance of KLF4 in the urine of patients with diabetic kidney disease(DKD),and to explore the relationship between KLF4 and the TCM pattern of kidney essence deficiency in DKD.Methods From January 2022 to March 2023,a total of 45 patients with stage Ⅲ-Ⅳ DKD,56 patients with type 2 diabetes mellitus(T2DM),and 44 healthy controls were enrolled at Dongzhimen Hospital affiliated with Beijing University of…查看全部>>
宿家铭;董昭熙;温雅轩;徐哲宇;于欣卉;梅洁;柳红芳
北京中医药大学东直门医院 北京 100700北京中医药大学东直门医院 北京 100700北京中医药大学东直门医院 北京 100700北京中医药大学东直门医院 北京 100700北京中医药大学东直门医院 北京 100700北京中医药大学东直门医院 北京 100700北京中医药大学东直门医院 北京 100700
中医学
糖尿病肾脏病KLF4"精损络痹"理论肾精亏虚证
diabetic kidney diseaseKLF4"essence deficiency leading to collaterals stagnation"theorykidney essence deficiency
《现代中医临床》 2024 (4)
8-13,6
北京中医药大学"揭榜挂帅"项目(No.2023-JYB-JBZD-023)
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