川北医学院学报2024，Vol.39Issue(7)：888-891,4.DOI:10.3969/j.issn.1005-3697.2024.07.005
血清高敏C反应蛋白/前白蛋白比值与急性ST段抬高型心肌梗死患者PCI术后冠状动脉无复流的相关性
Correlation between serum high-sensitivity C-reactive protein/prealbumin ratio and coronary no-reflow after PCI in patients with acute ST-segment elevation myocardial infarction
摘要
Abstract
Objective:To investigate the predictive value of high-sensitivity C-reactive protein/prealbumin(hs-CRP/PA)ratio for coronary no-reflow after PCI in patients with acute ST-segment elevation myocardial infarction(STEMI).Methods:A total of 98 pa-tients with acute STEMI were selected.The patients were divided into no-reflow group(n=25)and reflow group(n=73)according to the postoperative thrombolysis in myocardial infarction(TIMI)blood flow classification.Before PCI,the levels of serum hs-CRP and PA were detected,and the ratio of hs-CRP/PA was calculated.Logistic regression model was used to analyze the influencing factors of coro-nary no-reflow after PCI,and the receiver operating characteristic(ROC)curve was used to evaluate the predictive efficacy of hs-CRP/PA ratio on coronary no-reflow.Results:Compared with the reflow group,the serum PA level in the no-reflow group was lower(P＜0.05),and the LVEF,cTnI,BNP,hs-CRP and hs-CRP/PA ratio were higher(P＜0.05).Logistic regression analysis showed that preoperative LVEF,hs-CRP,PA and hs-CRP/PA ratio were independent related factors of coronary no-reflow after PCI(P＜0.05).ROC curve analysis showed that the AUC of hs-CRP/PA ratio in predicting coronary no-reflow after PCI in patients with acute STEMI was 0.802,which was higher than that of hs-CRP(AUC was 0.707)and PA(AUC was 0.642,P＜0.05).When the cutoff value was greater than 28.5,the sensitivity of hs-CRP/PA ratio was 88.0%and the specificity was 68.5%.Conclusion:Preoperative serum hs-CRP/PA ratio is an independent predictor of postoperative coronary no-reflow in patients with acute STEMI.Compared with a single in-dicator,it can better identify patients with high risk of coronary no-reflow.关键词
急性ST段抬高型心肌梗死/高敏C反应蛋白/前白蛋白/经皮冠状动脉介入治疗/无复流Key words
Acute ST segment elevation myocardial infarction/High-sensitivity C-reactive protein/Prealbumin/Percutaneous coronary intervention/No reflow分类
医药卫生引用本文复制引用
李相权,于宗良,张梦遥,王俊锋,王腾,陶宁超,张梓桑..血清高敏C反应蛋白/前白蛋白比值与急性ST段抬高型心肌梗死患者PCI术后冠状动脉无复流的相关性[J].川北医学院学报,2024,39(7):888-891,4.基金项目
国家自然科学基金项目(81700737) （81700737）
