低强度激光联合口腔正畸对牙周病致前牙移位患者疼痛及龈沟液ALP、AST、sICAM-1水平的影响OACSTPCD

Objective:To investigate the effect of low-intensity laser combined with orthodontic treatment on pain and levels of ALP,AST,and sICAM-1 in gingival crevicular fluid in patients with anterior tooth displacement caused by periodontal disease.Meth-ods:89 patients with anterior tooth displacement caused by periodontal disease were selected.They were divided into control group(n=44)and study group(n=45)according to the treatment methods.The control group received orthodontic treatment,while the study group received low-intensity laser treatment in combination with the control group,and both groups had a course of 3 months.The pain status[visual analog scale(VAS)score],tooth movement distance,tooth retraction speed,tooth looseness,and levels of ALP,AST,and sICAM-1 in gingival crevicular fluid were compared between two groups.Results:At 2 h,4 h,24 h,and 3 d after treatment,the VAS of the study group was lower than that of the control group(P＜0.05).After 7 d,14 d,28 d,and 3 m of treatment,the tooth movement distance of the study group was higher than that of the control group(P＜0.05).At 7,14,and 28 d after treatment,the tooth retraction speed of the study group was overtop than that of the control group(P＜0.05).After3 months of treatment,the expression levels of ALP,AST,and sICAM-1 in the gingival crevicular fluid of both groups increased compared to before treatment,but the study group was lower than the control group(P＜0.05).Conclusion:Combining low intensity laser therapy with orthodontic treatment is beneficial for accelerating anterior tooth displacement and movement caused by periodontal disease,and can effectively alleviate pain and periodontal inflammatory reactions.