川北医学院学报2024，Vol.39Issue(7)：960-964,5.DOI:10.3969/j.issn.1005-3697.2024.07.023
介入封堵术有效改善阻塞性睡眠呼吸暂停综合征合并卵圆孔未闭患者近期预后
Interventional occlusion effectively improves the recent prognosis of pa-tients with obstructive sleep apnea syndrome combined with patent fora-men ovale unclosed
摘要
Abstract
Objective:To explore the changes of clinical indexes in patients with obstructive sleep apnea syndrome(OSAS)combined with patent foramen ovale not closed(PFO)treated by interventional occlusion.Methods:37 patients with OSAS combined with PFO were selected as study subjects and grouped according to the different treatment modalities,in which the patients who under-went interventional occlusion were treated as the treatment group(n=19),and those who did not undergo interventional occlusion were treated as the control group(n=18).Changes in polysomnography(PSG),transthoracic echocardiography(TTE)and other relevant indexes were counted and compared between the two groups at 7 days and 3 months after surgery,respectively.Results:7days after sur-gery,the apnea hypoventilation index(AHI)and oxygen deceleration index(ODI)of the treatment group were lower than those of the control group(P＜0.05),the minimum oxygen saturation(SpO2)and average SpO2 of the treatment group were higher than those of the control group(P＜0.05).At3 months postoperatively,the AHI,maximum duration of apnea,maximum duration of hypoventilation,and ODI of the treatment group were lower than those of the control group(P＜0.05),the minimum SpO2 and average SpO2 were high-er than those of the control group(P＜0.05).Repeated-measurement analysis showed that the values of AHI and ODI in different peri-ods of the treatment group tended to decrease compared with those in the control group,and the difference was statistically significant(P＜0.05).At 3 months postoperatively,the right atrial left and right diameter(RALRD)and pulmonary artery pressure(PAP)were reduced compared with the preoperative period(P＜0.05).Conclusion:Interventional occlusion treatment of OSAS patients with PFO improves sleep breathing parameters,reduces the risk of hypoxemia and reduces pulmonary artery pressure.关键词
阻塞性睡眠呼吸暂停综合征/卵圆孔未闭/介入封堵术/多导睡眠监测/呼吸暂停低通气指数Key words
Obstructive sleep apnea syndrome/Patent foramen ovale/Interventional sealing/Polysomngraphy/Apnea hypoventilation index分类
医药卫生引用本文复制引用
田润琦,段鹏,苏峰,卫世强,段玉慧,刘会君,朱改针..介入封堵术有效改善阻塞性睡眠呼吸暂停综合征合并卵圆孔未闭患者近期预后[J].川北医学院学报,2024,39(7):960-964,5.基金项目
河南省新乡市科技攻关计划项目(GG2021048) （GG2021048）
