川北医学院学报2024，Vol.39Issue(8)：1026-1029,4.DOI:10.3969/j.issn.1005-3697.2024.08.005
功能性鼻内镜鼻腔鼻窦术后植入糖皮质激素鼻窦支架对慢性鼻窦炎鼻息肉术腔良性转归的影响
Influence of glucocorticoid sinus stent implantation after FESS on benign outcomes of surgical cavity in patients with CRSwNP
摘要
Abstract
Objective:To investigate the influence of glucocorticoid sinus stent implantation after functional endoscopic sinus surgery(FESS)on the benign outcomes of surgical cavity in patients with chronic rhinosinusitis with nasal polyp(CRSwNP).Meth-ods:A retrospective analysis was performed on patients with CRSwNP who were scheduled to undergo FESS.According to different sur-gical methods,they were divided into control group(n=55,routine surgical cavity cleaning after FESS surgery)and stent group(n=55,2 weeks after FESS surgery,perform surgical cavity cleaning and implant glucocorticoid sinus stent).The improvement of symptoms,pain level(VAS),endoscopic score(LKS),sinus outcome test score(SNOT),nasal mucosal eosinophil and goblet cell count levels,adverse reactions,and recurrence rate were compared between the two groups.Results:The postoperative improvement of patients in the stent group was better than that in the control group(P＜0.05).The postoperative VAS,LKS,and SNOT scores of both groups of pa-tients showed a significant downward trend 4,8,and 12 weeks postoperatively(P＜0.05),and the postoperative scores of the stent group were lower than those of the control group(P＜0.05).After 6 months of surgery,the eosinophil count of the nasal mucosa in both groups decreased(P＜0.05),and the stent group was lower than the control group(P＜0.05).The goblet cell count increased(P＜0.05),and the scaffold group was lower than the control group(P＜0.05).There was no statistically significant difference in ad-verse reactions between the two groups of drugs(P＞0.05).There were 3 relapses in the stent group(5.45％)and 10 relapses in the control group(18.18％),with statistically significant differences(x2=4.274,P=0.039).Conclusion:Glucocorticoid sinus stent im-plantation after FESS can significantly improve the clinical symptoms and reduce the recurrence rate in CRSwNP patients.It has positive significance for the benign outcomes of surgical cavity.关键词
慢性鼻窦炎鼻息肉/功能性鼻内镜鼻腔鼻窦术/糖皮质激素鼻窦支架/嗜酸性粒细胞Key words
Chronic rhinosinusitis with nasal polyp/Functional endoscopic sinus surgery/Glucocorticoid sinus stent/Eosinophil分类
医药卫生引用本文复制引用
侯薇,袁浩展,王艳婷..功能性鼻内镜鼻腔鼻窦术后植入糖皮质激素鼻窦支架对慢性鼻窦炎鼻息肉术腔良性转归的影响[J].川北医学院学报,2024,39(8):1026-1029,4.基金项目
陕西省国际合作重点项目(No.2020kwz-019) （No.2020kwz-019）
