长春中医药大学学报2024,Vol.40Issue(7):775-778,4.DOI:10.13463/j.cnki.cczyy.2024.07.015
防己黄芪汤联合丹参饮治疗脾肾气虚型慢性肾衰并发心衰患者肾脏血流、心功能的影响
The effect of Fangji Huangqi decoction combined with Dan Shen decoction on kidney blood flow and cardiac function in patients with chronic renal failure and heart failure of qi deficiency in spleen and kidney-type
摘要
Abstract
Objective To explore the effect of Fangji Huangqi decoction combined with Dan Shen decoction on kidney blood flow and cardiac function in patients with chronic renal failure and heart failure of qi deficiency in spleen and kidney-type.Methods 82 patients with chronic renal failure and heart failure of qi deficiency in spleen and kidney-type admitted to Fangshan Hospital of Beijing University of Chinese Medicine from June 2020 to June 2022 were selected and divided into the control group(n=40)and and the combination group(n=42)according to the treatment method.The control group was treated with Dan Shen decoction,and the combination group was treated with Fangji Huangqi decoction combined with Dan Shen decoction.Traditiional Chinese medicine(TCM)syndrome scores of the patients were evaluated;The renal function,levels of inflammatory factors,renal blood flow,and cardiac function before and after treatment in both groups were compared.Results After treatment,compared with before treatment,TCM syndrome scores,renal function,levels of inflammatory factors,and renal blood flow decreased,and the degree of decrease in the combination group was lower than that in the control group(P<0.05).After treatment,the comparison of cardiac function between two groups showed that left ventricular ejection fraction(LVEF)increased,and left ventricular end systolic volume(LVESV)and left ventricular end diastolic diameter(LVEDD)decreased,and the combination group was better than the control group(P<0.05).Conclusion After the treatment of Fangji Huangqi decoction combined with Dan Shen decoction,TCM syndrome scores in patients with chronic renal failure and heart failure of qi deficiency in spleen and kidney-type decrease.This therapy can improve renal function,the levels of inflammatory factors,renal blood flow,and cardiac function of the patients.This therapy has significant advantages and is worth promoting and applying.关键词
防己黄芪汤/丹参饮/脾肾气虚型慢性肾衰并发心衰/肾脏血流/心功能Key words
Fangji Huangqi decoction/Dan Shen decoction/chronic renal failure and heart failure of qi deficiency in spleen and kidney-type/kidney blood flow/cardiac function分类
医药卫生引用本文复制引用
徐立彦,陈伟涛,张大伟..防己黄芪汤联合丹参饮治疗脾肾气虚型慢性肾衰并发心衰患者肾脏血流、心功能的影响[J].长春中医药大学学报,2024,40(7):775-778,4.基金项目
北京市科技发展计划项目(202003051987) (202003051987)