磁共振成像2024，Vol.15Issue(6)：87-93,7.DOI:10.12015/issn.1674-8034.2024.06.013
Kaiser评分与表观扩散系数对哺乳期乳腺良恶性病变的鉴别诊断效能研究
Study on the differential diagnostic efficacy of Kaiser score and apparent diffusion coefficient values for benign and malignant breast lesions during lactation
摘要
Abstract
Objective: To evaluate the diagnostic performance of Kaiser score and apparent diffusion coefficient (ADC) in the differential diagnosis of benign and malignant breast lesions during lactation. Materials and Methods: This retrospective study enrolled 65 patients who underwent breast MRI in the Third Affiliated Hospital of Zhengzhou University from October 2016 to October 2023. The clinical, pathological and imaging data of 65 patients were collected. According to the pathological results, the cases were divided into malignant group (31 cases) and benign group (34 cases). One primary lesion was selected from each patient for Kaiser score and ADC value measurement. Lesions with Kaiser scores greater than 4 were reevaluated based on their ADC values, and new predictive indicator Kaiser+ were obtained. Using pathological results as the gold standard, and receiver operating characteristic (ROC) curve was used to compare the diagnostic accuracy of ADC value. Calculated the area under the curve (AUC), sensitivity, specificity, and accuracy, and compared the AUC of the three using DeLong test. Results: The AUC of ADC value was 0.818 [95％ confidence interval (CI): 0.709-0.927]. The AUC of Kaiser score was 0.881 (95％ CI: 0.791-0.971). The AUC of Kaiser+ score was 0.910 (95％ CI: 0.931-0.990). The AUC between Kaiser+ score and ADC value was statistically significant (0.910 vs. 0.818, P=0.011). There was no significant difference in AUC between Kaiser score and ADC value (0.881 vs. 0.818, P=0.141), and there was no significant difference in AUC between Kaiser+ score and Kaiser score (0.910 vs. 0.881, P=0.151). Conclusions: Kaiser+ score has higher diagnostic efficiency than ADC value, which can accurately identify benign and malignant breast lesions during lactation and provide reference for clinical development of personalized treatment plans.关键词
哺乳期乳腺癌/鉴别诊断/Kaiser评分/表观扩散系数/磁共振成像Key words
breast cancer during lactation/differential diagnosis/Kaiser score/apparent diffusion coefficient/magnetic resonance imaging分类
医药卫生引用本文复制引用
杨喆璇,赵鑫,谭世芳,程美英,沈艳勇,张晓雪,冯占起,王长浩..Kaiser评分与表观扩散系数对哺乳期乳腺良恶性病变的鉴别诊断效能研究[J].磁共振成像,2024,15(6):87-93,7.基金项目
天健先进生物医学实验室立项资助项目Project Funding for Tianjian Advanced Biomedical Laboratory. （）
