针刺四关穴治疗轻度认知障碍多模态MRI研究进展
Progress in multimodal MRI research on acupuncture at Siguan point for the treatment of mild cognitive impairment
摘要
Abstract
Mild cognitive impairment (MCI) is the early stage of Alzheimer's disease (AD), characterized by decreased learning and memory abilities, with no impact on daily life. Acupuncture at Siguan point has a definite therapeutic effect on MCI and is widely used in clinical practice; acupuncture can improve cognitive function, but the principle of action is complex. Multimodal MRI provides visual support for the study of brain effects and efficacy assessment of acupuncture at the Siguan point in the treatment of MCI due to its advantages of precise localization and real-time observation of abnormal brain regions.In this article, structural MRI (sMRI), diffusion tensor imaging (DTI), blood oxygen level dependent functional magnetic resonance imaging (BOLD-fMRI), magnetic resonance spectroscopy (MRS), and arterial spin labeling (ASL) were introduced to review the literature on cerebral structure, function, metabolism and blood perfusion of MCI treated by acupuncture at Siguan point. The intracerebral changes of MCI were discussed from multiple perspectives and the mechanism of acupuncture treatment was analyzed, it provides new ideas for the follow-up research of MCI.关键词
阿尔茨海默病/轻度认知障碍/针刺四关穴/磁共振成像/结构磁共振成像/功能磁共振成像/弥散张量成像/磁共振波谱/动脉自旋标记分类
医药卫生引用本文复制引用
韩盛旺,李晓陵,王杨,侯玉,魏泽宜,高胜兰,王珑..针刺四关穴治疗轻度认知障碍多模态MRI研究进展[J].磁共振成像,2024,15(6):138-143,6.基金项目
国家自然科学基金项目(编号:82074537、81303044) （编号:82074537、81303044）
黑龙江省自然科学基金联合引导项目(编号:LH2020H103、LH2022H082) （编号:LH2020H103、LH2022H082）
黑龙江省卫生健康委科研项目(编号:20222020011109) （编号:20222020011109）
黑龙江省中医药学会青年人才托举工程项目(编号:2022-QNRC1-31) （编号:2022-QNRC1-31）
黑龙江中医药大学研究生创新科研项目(编号:2023yjscx30)National Natural Science Foundation of China (No.82074537,81303044) （编号:2023yjscx30）
Natural Science Foundation Project of Heilongjiang Province (No.LH2020H103,LH2022H082) （No.LH2020H103,LH2022H082）
Research Project of Heilongjiang Provincial Health Commission(No.20222020011109) （No.20222020011109）
Young Talent Support Project of Heilongjiang Provincial Association of Traditional Chinese Medicine (No.2022-QNRC1-31) （No.2022-QNRC1-31）
Graduate Innovative Research Project of Heilongjiang University of Chinese Medicine (No.2023yjscx30). （No.2023yjscx30）
