磁共振成像2024，Vol.15Issue(6)：159-165,7.DOI:10.12015/issn.1674-8034.2024.06.025
ATN诊断框架下阿尔茨海默病的PET/MR研究进展
Research progress in PET/MR for diagnosis of Alzheimer's disease within ATN framework
摘要
Abstract
Alzheimer's disease (AD), a leading cause of dementia, emphasizes the critical importance of early diagnosis for timely intervention and disease progression mitigation. In 2018, the National Institute of Aging and Alzheimer's Association (NIA-AA) introduced the ATN (amyloid/tau/neurodegeneration) diagnostic criteria for AD, which has garnered extensive clinical acceptance and utilization. This article offers a comprehensive review of the applications of positron emission tomography (PET), magnetic resonance imaging (MRI), and integrated positron emission tomography-magnetic resonance imaging (PET/MR) in the ATN diagnostic framework, and explores the profound advantages of multi-probe, multi-modal PET/MR in diagnosis. The objective is to provide researchers with novel perspectives and references for further investigation, drive the clinical application of PET/MR for AD patients, and furnish clinicians with crucial imaging evidence to support their practice关键词
阿尔茨海默病/生物标志物/正电子发射断层显像/磁共振成像/多模态成像Key words
Alzheimer's disease/biomarkers/positron emission tomography/magnetic resonance imaging/multimodal imaging分类
医药卫生引用本文复制引用
周妍,周琦东,尹晨茹,毋若琳,盖永康,苏颖,夏晓天..ATN诊断框架下阿尔茨海默病的PET/MR研究进展[J].磁共振成像,2024,15(6):159-165,7.基金项目
科技部科技创新2030-"脑科学与类脑研究"重大项目(编号:2022ZD0211800) （编号:2022ZD0211800）
湖北省自然科学基金项目(编号:2024AFB633)Science and Technology Innovation 2030-"Brain Science and Brain like Research" Major Project of the Ministry of Science and Technology (No.2022ZD0211800) （编号:2024AFB633）
Hubei Provincial Natural Science Foundation Project (No.2024AFB633). （No.2024AFB633）
