磁共振成像2024,Vol.15Issue(6):185-189,5.DOI:10.12015/issn.1674-8034.2024.06.029
扩散磁共振成像振荡梯度自旋回波原理及其在脑胶质瘤中的应用进展
The principle of oscillating gradient spin echo in diffusion magnetic resonance imaging and its application in gliomas
摘要
Abstract
Gliomas are the most common primary central nervous system tumors in adults with high mortality rate and strong invasiveness. The tumor grading and genetic phenotype heterogeneity of gliomas will affect the formulation of treatment plans and prognosis inference. Post-treatment efficacy evaluation and early diagnosis of tumor recurrence can help improve patient survival. Diffusion magnetic resonance imaging based on oscillatory gradient spin echo (OGSE) is a novel diffusion MRI technique that has broad application prospects in the imaging diagnosis of gliomas by detecting microstructure features, such as cell diameter, cell density, intracellular and extracellular volume fraction. This paper reviewed the technical principles of OGSE imaging, research progress in classification, prediction of molecular type, response evaluation and differential diagnosis of brain glioma and limitations of OGSE imaging applications, providing a new perspective for preoperative diagnosis and postoperative evaluation of glioblastoma.关键词
脑胶质瘤/振荡梯度自旋回波/扩散磁共振成像/磁共振成像/微结构成像/肿瘤分级/分子分型预测/疗效评估Key words
glioma/oscillating gradient spin echo/diffusion magnetic resonance imaging/magnetic resonance imaging/microstructure imaging/tumor grading/molecular typing prediction/response evaluation分类
医药卫生引用本文复制引用
陆珏,汪晶..扩散磁共振成像振荡梯度自旋回波原理及其在脑胶质瘤中的应用进展[J].磁共振成像,2024,15(6):185-189,5.基金项目
国家自然科学基金项目(编号:82371945)National Natural Science Foundation of China (No.82371945). (编号:82371945)