分析化学2024，Vol.52Issue(6)：838-845,8.DOI:10.19756/j.issn.0253-3820.241066
扇形纸喷雾离子化-小型便携式质谱法现场快速筛查含植物提取物类化妆品中6种农药残留
Rapid On-Site Screening of Six Kinds of Pesticide Residues in Cosmetics Containing Plant Extracts by Fan-shaped Paper Spray Ionization and Miniature Mass Spectrometry
摘要
Abstract
Cosmetics containing plant extracts may pose health risks to consumers due to inadequate control over the quality of plant raw materials,which may lead to residues of pesticides such as carbendazim in cosmetics. Developing rapid detection methods is of paramount importance for regulating product quality and safeguarding human health. A rapid on-site analytical method was developed for the screening of six kinds of pesticide residues in plant extract-based cosmetics using fan-shaped paper spray ionization with chromatographic enrichment functionality coupled with a miniature mass spectrometer. Cosmetic samples were directly loaded onto the fan-shaped paper substrate drop by drop,followed by chromatographic enrichment,paper spray ionization,and the miniature mass spectrometry analysis. The entire analysis time for a single run was less than 1 min. By loading samples in a dropwise manner,significantly improved chromatographic enrichment on the tip and 6 to 32-fold signal enhancement were achieved on the fan-shaped paper substrate compared to traditional triangle-shaped paper substrate. The limits of detection (LODs) and quantitation (LOQs) for the six kinds of pesticides were 0.02-0.05 mg/kg and 0.05-0.10 mg/kg,respectively. The recoveries were 82.6％-101.8％ with relative standard deviations of 8.3％-16.5％. The established method was convenient,sensitive,and suitable for rapid,on-site screening of pesticide residues in plant extract-based cosmetics.关键词
层析富集/扇形纸喷雾离子化/小型便携式质谱/农药残留/现场快速筛查Key words
Chromatographic enrichment/Fan-shaped paper spray ionization/Miniature mass spectrometry/Pesticide residues/Rapid on-site screening引用本文复制引用
吕悦广,赵佳宇,薛宏宇,马强..扇形纸喷雾离子化-小型便携式质谱法现场快速筛查含植物提取物类化妆品中6种农药残留[J].分析化学,2024,52(6):838-845,8.基金项目
国家市场监督管理总局技术保障专项项目(No.2023YJ08)资助.Supported by the Science and Technology Program Project of State Administration for Market Regulation(No.2023YJ08). （No.2023YJ08）
