分子影像学杂志2024，Vol.47Issue(6)：644-648,5.DOI:10.12122/j.issn.1674-4500.2024.06.15
3.0T MRI在儿童癫痫疾病的临床应用价值
Clinical application value of 3.0T MRI in pediatric epilepsy
摘要
Abstract
Objective To investigate the clinical application value of GE 3.0T SIGNA Architect multimodal MRI technology in children with epilepsy. Methods A retrospective analysis was performed on 110 MRI patients aged from 0 to 12 years old who were clinically diagnosed with epilepsy in Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region from June 2021 to April 2024, including 58 males and 52 females, aged at 6.15±0.66 years old. Patients were divided into two groups according to different examination of inspection equipment. Group A (Philips 1.5T Achieva, n=55) underwent sagittal T2WI, axial T1WI, T2WI, T2 FLAIR, and DWI sequences, focusing on gray matter structure, gyral sulci development, temporal hippocampus structure and volume, and craniocerebral signals. Group B (GE 3.0T SIGNA Architect, n=55) underwent a more comprehensive set of scans including axial whole-brain BRAVO T1, axial CUBE T2 FLAIR, axial T2WI bilateral hippocampus, sagittal T2WI, axial MUSE DWI, ASL, DTI sequences, and MRS monomer or polyvoxel scanning. Gray matter structure, gyri sulci development, temporal hippocampus structure size and volume, craniocerebral signal, ASL perfusion, DTI nerve cellulose and FA value increase and decrease, MRS Metabolites spectrum line increase and decrease were observed. Results In group A, 5 cases of hippocampal sclerosis/shrinkage (9.1％), 6 cases of cortical dysplasia (10.9％), 6 cases of autoimmune encephalitis (10.9％), 3 cases of giant gyrus malformation (5.5％); In group B, 15 cases of hippocampal sclerosis/shrinkage (27.3％), 16 cases of cortical dysplasia (29.1％), 14 cases of autoimmune encephalitis (25.5％), 10 cases of macrogyrus malformation (18.2％), 23 cases of abnormal ASL perfusion (41.8％), and 9 cases of abnormal bopp metabolism (16.4％). Diffusion tensor imaging abnormalities decreased by 5 cases (9.1％).The diagnostic differences of hippocampal sclerosis/shrinkage in cephalic epilepsy, cortical dysplasia, autoimmune encephalitis, giant gyri malformation, ASL perfusion, MRS, DTI between group A and group B were statistically significant (P<0.05). Conclusion 3.0T multimodal MRI scanning technique has a more comprehensive and accurate image evaluation of brain morphology and function in patients with epilepsy.关键词
癫痫/磁共振成像/皮层发育不良/海马/波谱成像/内源性动脉自选标记/扩散张量Key words
epilepsy/magnetic resonance imaging/cortical dysplasia/hippocampus/spectral imaging/endogenous arterial self selection markers/diffusion tensor引用本文复制引用
陈辉艳,梁莎,王映飞,马慧,黄华驰,黄卫保..3.0T MRI在儿童癫痫疾病的临床应用价值[J].分子影像学杂志,2024,47(6):644-648,5.基金项目
广西壮族自治区卫生健康委员会自筹科研课题(Z20200997) （Z20200997）
