重症支原体肺炎患儿铁死亡水平与炎症反应、氧化应激的相关性及意义OACSTPCD
Correlations of serum ferroptosis level with inflammatory response and oxidative stress in children with severe Mycoplasma pneumonia and their significance
目的 研究重症支原体肺炎(MPP)患儿铁死亡水平与炎症反应、氧化应激的相关性及意义.方法 选择2019年6月至2022年6月我院儿科收治的74例轻症 MPP患儿和136重症 MPP患儿,分别作为轻症 MPP组和重症 MPP组,另选择80例健康儿童作为对照组.采集血清并检测铁死亡标志物转铁蛋白受体1(TfR1)、酰基辅酶A合成酶长链家族成员4(ACSL4)、谷胱甘肽过氧化物酶4(GPX4)、炎症反应标志物C反应蛋白(CRP)、白介素-6(IL-6)…查看全部>>
Objective To study correlations of serum level of ferroptosis with inflammatory response and oxidative stress in children with severe Mycoplasma pneumonia(MPP)and their significance.Methods 74 children with mild MPP and 136 children with severe MPP who admitted to our Department of Pediatrics from June 2019 to June 2022 were selected as the mild MPP group and the severe MPP group respectively,and 80 healthy children were selected as the control group.Serum s…查看全部>>
郑艳兰;谢姣;卢美娟
衡阳市妇幼保健院儿童重症医学科,湖南衡阳 421000衡阳市妇幼保健院儿童重症医学科,湖南衡阳 421000衡阳市妇幼保健院儿童重症医学科,湖南衡阳 421000
预防医学
肺炎支原体肺炎铁死亡炎症反应氧化应激相关性诊断
Mycoplasma pneumoniae pneumoniaferroptosisinflammatory reactionsoxidative stresscorrelationdiagnosis
《中国妇幼健康研究》 2024 (7)
32-37,6
衡阳市科学技术局(S2018N9031034365)
评论