国际医学放射学杂志2024，Vol.47Issue(4)：401-406,411,7.DOI:10.19300/j.2024.Z21381
化疗相关认知功能障碍的MRI研究进展
Advances in MRI research on chemotherapy-related cognitive impairment
摘要
Abstract
Chemotherapy-related cognitive impairment(CRCI)significantly impacts the life quality of cancer patients,and its neurobiological mechanism have garnered widespread attention.Multimodal magnetic resonance imaging(MRI),including structural MRI,functional MRI,arterial spin labeling(ASL),and magnetic resonance spectrum(MRS),can reflect the structural,functional,metabolic,and perfusion information of the brain,revealing the imaging mechanisms of the effects of chemotherapy drugs on cognitive function.Commonly used chemotherapeutic drugs,including anthracyclines,non-anthracyclines,and platinum-based compounds,can induce CRCI.This paper briefly reviews the potential molecular biology mechanisms of CRCI induced by different chemotherapy drugs,and summarizes the research progress of multimodal MRI technology in the structural and functional changes of the CRCI patients'brain.关键词
化疗相关认知功能障碍/磁共振成像/化疗药物Key words
Chemotherapy-related cognitive impairment/Magnetic resonance imaging/Chemotherapeutic drugs分类
医药卫生引用本文复制引用
胡蓝月,殷信道,陈宇辰..化疗相关认知功能障碍的MRI研究进展[J].国际医学放射学杂志,2024,47(4):401-406,411,7.基金项目
江苏省自然科学基金面上项目(BK20211008) （BK20211008）
